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ONTOLOGY REPORT - ANNOTATIONS

Term:ERCC4-ERCC1 complex
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Accession:GO:0070522 term browser browse the term
Definition:A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.
Comment:Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.
Synonyms:exact_synonym: Rad1-Rad10 complex;   XPF-ERCC1 complex


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ERCC4-ERCC1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit located_in
part_of		 ISO
IEA		 (PMID:16076955) ComplexPortal
Ensembl
TreeGrafter		 PMID:16076955 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:51,783,537...51,808,898
Ensembl chr 6:51,783,478...51,798,984 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit located_in
part_of		 ISO
IEA		 (PMID:16076955) ComplexPortal
Ensembl		 PMID:16076955 GO_REF:0000107 NCBI chr 3:29,266,234...29,306,109
Ensembl chr 3:29,269,989...29,306,151 		JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit part_of
located_in		 IEA
ISO		 (PMID:19595721), (PMID:19596235), (PMID:19596236) Ensembl
UniProt		 PMID:19595721 PMID:19596235 PMID:19596236 GO_REF:0000107 NCBI chr 3:38,646,904...38,670,173
Ensembl chr 3:38,646,938...38,670,168 		JBrowse link
G VCAN versican part_of ISO (MGI:3758502|PMID:14690602) BHF-UCL PMID:14690602 MGI:3758502 NCBI chr 2:91,358,348...91,643,697
Ensembl chr 2:91,384,391...91,811,208 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18687
    protein-containing complex 6005
      nuclear protein-containing complex 1244
        nucleotide-excision repair complex 13
          ERCC4-ERCC1 complex 5
Path 2
Term Annotations click to browse term
  cellular_component 18687
    cellular anatomical entity 18466
      organelle 12444
        membrane-bounded organelle 11406
          intracellular membrane-bounded organelle 10861
            nucleus 6843
              nuclear protein-containing complex 1244
                nucleotide-excision repair complex 13
                  ERCC4-ERCC1 complex 5
paths to the root