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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein K48-linked ubiquitination
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Accession:GO:0061944 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


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negative regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppia peptidylprolyl isomerase A involved_in ISO (PMID:30328013) UniProt PMID:30328013 NCBI chrNW_004624740:7,447,554...7,450,707
Ensembl chrNW_004624740:7,447,554...7,450,641
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G Trim44 tripartite motif containing 44 involved_in ISO (PMID:23460740) BHF-UCL PMID:23460740 NCBI chrNW_004624767:11,373,992...11,550,622
Ensembl chrNW_004624767:11,378,172...11,550,337
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    metabolic process 9085
      macromolecule metabolic process 7258
        protein metabolic process 3621
          protein modification process 1801
            post-translational protein modification 787
              protein modification by small protein conjugation or removal 751
                negative regulation of protein modification by small protein conjugation or removal 75
                  negative regulation of protein ubiquitination 62
                    negative regulation of protein polyubiquitination 7
                      negative regulation of protein K48-linked ubiquitination 2
Path 2
Term Annotations click to browse term
  biological_process 15093
    metabolic process 9085
      macromolecule metabolic process 7258
        protein metabolic process 3621
          protein modification process 1801
            post-translational protein modification 787
              protein modification by small protein conjugation or removal 751
                protein modification by small protein conjugation 673
                  protein ubiquitination 609
                    protein polyubiquitination 254
                      protein K48-linked ubiquitination 88
                        regulation of protein K48-linked ubiquitination 6
                          negative regulation of protein K48-linked ubiquitination 2
paths to the root