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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA-3-methylguanine glycosylase activity
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Accession:GO:0052822 term browser browse the term
Definition:Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.
Synonyms:xref: EC:3.2.2.21


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DNA-3-methylguanine glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G MPG N-methylpurine DNA glycosylase enables IEA UniProt GO_REF:0000003 NCBI chr 5:35,073...42,290
Ensembl chr 5:35,114...43,581
JBrowse link
G P MPG N-methylpurine DNA glycosylase enables IEA UniProt GO_REF:0000003 NCBI chr 3:41,540,650...41,548,339
Ensembl chr 3:41,540,656...41,548,290
JBrowse link
G S Mpg N-methylpurine DNA glycosylase enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936501:783,408...791,109
Ensembl chrNW_004936501:783,475...791,146
JBrowse link
G B MPG N-methylpurine DNA glycosylase enables IEA UniProt GO_REF:0000003 Ensembl chr16:70,655...76,763 JBrowse link
G R Mpg N-methylpurine-DNA glycosylase enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G M Mpg N-methylpurine-DNA glycosylase enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700
JBrowse link
G H MPG N-methylpurine DNA glycosylase enables IEA UniProt GO_REF:0000003 NCBI chr16:77,007...85,846
Ensembl chr16:77,007...85,851
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 189980
    catalytic activity 54016
      catalytic activity, acting on a nucleic acid 5832
        catalytic activity, acting on DNA 2374
          DNA N-glycosylase activity 134
            alkylbase DNA N-glycosylase activity 10
              DNA-3-methylbase glycosylase activity 7
                DNA-3-methylguanine glycosylase activity 7
Path 2
Term Annotations click to browse term
  molecular_function 189980
    catalytic activity 54016
      hydrolase activity 22775
        hydrolase activity, acting on glycosyl bonds 1221
          hydrolase activity, hydrolyzing N-glycosyl compounds 301
            DNA N-glycosylase activity 134
              alkylbase DNA N-glycosylase activity 10
                DNA-3-methylbase glycosylase activity 7
                  DNA-3-methylguanine glycosylase activity 7
paths to the root