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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cyclic-nucleotide phosphodiesterase activity
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Accession:GO:0051344 term browser browse the term
Definition:Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms:exact_synonym: 3',5' cyclic nucleotide phosphodiesterase inhibitor;   down regulation of cyclic nucleotide phosphodiesterase activity;   downregulation of cyclic nucleotide phosphodiesterase activity;   negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity
 narrow_synonym: 3',5'-cyclic-AMP phosphodiesterase inhibitor;   cAMP phosphodiesterase inhibitor;   inhibition of cyclic nucleotide phosphodiesterase activity;   negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity;   negative regulation of cAMP phosphodiesterase activity;   negative regulation of cGMP phosphodiesterase activity
 related_synonym: phosphodiesterase inhibitor


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negative regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGLN1 egl-9 family hypoxia inducible factor 1 involved_in ISO PMID:22975349 RGD
BHF-UCL		 PMID:22975349 RGD:8554232 NCBI chr 1:206,915,541...206,976,656 JBrowse link
G RGN regucalcin ISO RGD PMID:1656206 RGD:9590243 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
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  biological_process 19317
    biological regulation 11878
      regulation of molecular function 1528
        negative regulation of molecular function 564
          negative regulation of catalytic activity 331
            negative regulation of hydrolase activity 100
              negative regulation of cyclic-nucleotide phosphodiesterase activity 2
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