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ONTOLOGY REPORT - ANNOTATIONS
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Term:
prostaglandin-E synthase activity
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Accession:
GO:0050220
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Definition:
Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).
Synonyms:
related_synonym:
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity; PGE isomerase activity; PGE2 isomerase activity; PGH-PGE isomerase activity; Prostaglandin-H(2) E-isomerase activity; endoperoxide isomerase activity; prostaglandin H-E isomerase activity; prostaglandin R-prostaglandin E isomerase activity; prostaglandin endoperoxide E isomerase activity; prostaglandin endoperoxide E2 isomerase activity; prostaglandin-H2 E-isomerase activity
xref:
EC:5.3.99.3; KEGG_REACTION:R02265; MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN; RHEA:12893; reactome:R-HSA-2161660 "PGH2 is isomerised to PGE2 by PTGES"; reactome:R-HSA-265295 "Prostaglandin E synthase isomerizes PGH2 to PGE2"
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Rat (4)
Mouse (4)
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Chinchilla (3)
Bonobo (4)
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Squirrel (4)
Pig (3)
Green Monkey (2)
Naked Mole-rat (3)
All
Genes (4)
prostaglandin-E synthase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ptges
prostaglandin E synthase
enables
IDA
IBA
ISO
GO_REF:0000033
(PMID:18682561)
GO_Central
RGD
PMID:18682561
PMID:11067848
GO_REF:0000033,
RGD:67929
NCBI chr 3:14,177,892...14,189,236
G
Ptges2
prostaglandin E synthase 2
enables
ISO
IBA
(PMID:12804604)
GO_REF:0000033
RGD
GO_Central
PMID:12804604
GO_REF:0000033
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
G
Ptges3
prostaglandin E synthase 3
enables
IDA
ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:10922363)
GO_REF:0000104
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:10922363
PMID:10922363
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104,
RGD:5688071
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
G
Ptges3l1
prostaglandin E synthase 3-like 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr X:42,215,200...42,224,472
Ensembl chr X:42,214,756...42,225,047
Term paths to the root
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Path 1
Term
Annotations
molecular_function
20811
catalytic activity
6119
isomerase activity
220
intramolecular oxidoreductase activity
76
prostaglandin-E synthase activity
4