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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidic acid metabolic process
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Accession:GO:0046473 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
Synonyms:exact_synonym: phosphatidic acid metabolism

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phosphatidic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkb diacylglycerol kinase beta involved_in ISO PMID:23949095 UniProt PMID:23949095 RGD:30309912 NCBI chrNW_004624739:15,185,294...15,821,293
Ensembl chrNW_004624739:15,186,115...15,821,907 		JBrowse link
G Dgkh diacylglycerol kinase eta involved_in ISO (PMID:23949095) BHF-UCL PMID:23949095 NCBI chrNW_004624748:12,850,476...13,065,504
Ensembl chrNW_004624748:12,862,946...13,065,484 		JBrowse link
G Lipc lipase C, hepatic type ISO RGD PMID:2223857 RGD:1600650 NCBI chrNW_004624781:13,342,469...13,468,120
Ensembl chrNW_004624781:13,342,357...13,455,055 		JBrowse link
G Lpin1 lipin 1 involved_in ISO (PMID:20231281) UniProt PMID:20231281 NCBI chrNW_004624865:4,220,047...4,258,014
Ensembl chrNW_004624865:4,219,081...4,258,448 		JBrowse link
G Pla2g10 phospholipase A2 group X involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624782:3,871,034...3,887,476
Ensembl chrNW_004624782:3,870,940...3,887,426 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO (PMID:9032461) BHF-UCL PMID:9032461 NCBI chrNW_004624764:5,144,549...5,152,517
Ensembl chrNW_004624764:5,144,549...5,151,995 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:28947740) UniProt PMID:28947740 NCBI chrNW_004624747:7,602,848...7,607,872
Ensembl chrNW_004624747:7,603,277...7,607,753 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004624865:4,220,047...4,258,014
Ensembl chrNW_004624865:4,219,081...4,258,448 		JBrowse link
phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624825:9,088,907...9,101,474
Ensembl chrNW_004624825:9,088,957...9,102,419 		JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:76,414,732...76,436,177
Ensembl chrNW_004624730:76,414,626...76,436,156 		JBrowse link
G Abhd8 abhydrolase domain containing 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624908:641,181...648,366
Ensembl chrNW_004624908:641,841...647,877 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9299423) MGI
TreeGrafter		 PMID:9299423 GO_REF:0000118 NCBI chrNW_004624754:24,145,349...24,151,731
Ensembl chrNW_004624754:24,145,919...24,155,278 		JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in ISO (PMID:9212163) BHF-UCL PMID:9212163 NCBI chrNW_004624760:1,746,642...1,755,154
Ensembl chrNW_004624760:1,747,081...1,755,113 		JBrowse link
G Dgka diacylglycerol kinase alpha involved_in ISO (PMID:15544348), (PMID:2175712), (PMID:22627129)
(PMID:23949095)		 UniProt PMID:2175712 PMID:15544348 PMID:22627129 PMID:23949095 NCBI chrNW_004624802:12,092,949...12,115,472
Ensembl chrNW_004624802:12,093,196...12,110,227 		JBrowse link
G Dgkb diacylglycerol kinase beta involved_in ISO PMID:23949095 UniProt PMID:23949095 RGD:30309912 NCBI chrNW_004624739:15,185,294...15,821,293
Ensembl chrNW_004624739:15,186,115...15,821,907 		JBrowse link
G Dgkd diacylglycerol kinase delta involved_in ISO (PMID:17880279), (PMID:23949095) UniProt PMID:17880279 PMID:23949095 NCBI chrNW_004624843:5,879,335...5,959,525
Ensembl chrNW_004624843:5,899,538...5,957,422 		JBrowse link
G Dgke diacylglycerol kinase epsilon involved_in ISO (PMID:15544348), (PMID:19744926), (PMID:22108654) UniProt PMID:15544348 PMID:19744926 PMID:22108654 NCBI chrNW_004624795:11,908,738...11,934,403
Ensembl chrNW_004624795:11,908,793...11,933,125 		JBrowse link
G Dgkg diacylglycerol kinase gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:70,412,477...70,599,664
Ensembl chrNW_004624730:70,412,585...70,597,606 		JBrowse link
G Dgkh diacylglycerol kinase eta involved_in ISO (PMID:27643686) UniProt PMID:27643686 NCBI chrNW_004624748:12,850,476...13,065,504
Ensembl chrNW_004624748:12,862,946...13,065,484 		JBrowse link
G Dgki diacylglycerol kinase iota involved_in ISO PMID:15024004 UniProt PMID:15024004 RGD:1302915 NCBI chrNW_004624765:17,663,347...18,128,007
Ensembl chrNW_004624765:17,669,645...18,124,967 		JBrowse link
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:23610160), (PMID:23767959)
(PMID:22732145), (PMID:23949095), (PMID:9099683)		 ParkinsonsUK-UCL PMID:9099683 PMID:22732145 PMID:23610160 PMID:23767959 PMID:23949095 NCBI chrNW_004624755:26,179,099...26,197,764
Ensembl chrNW_004624755:26,179,162...26,189,901 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (PMID:15544348), (PMID:19744926)
(PMID:12883552), (PMID:27739494)		 UniProt PMID:12883552 PMID:15544348 PMID:19744926 PMID:27739494 NCBI chrNW_004624767:2,173,774...2,210,304
Ensembl chrNW_004624767:2,173,272...2,210,279 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in ISO PMID:22905194 UniProt PMID:22905194 RGD:30309909 NCBI chrNW_004624737:34,198,773...34,268,815
Ensembl chrNW_004624737:34,198,518...34,265,192 		JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial involved_in ISO (PMID:22905194) UniProt PMID:22905194 NCBI chrNW_004624749:2,152,755...2,161,139
Ensembl chrNW_004624749:2,153,112...2,160,745 		JBrowse link
G Pld1 phospholipase D1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18519738 MGI
InterPro		 PMID:18519738 GO_REF:0000002 RGD:8554572 NCBI chrNW_004624730:49,665,432...49,885,242
Ensembl chrNW_004624730:49,665,432...49,885,184 		JBrowse link
G Pld2 phospholipase D2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624786:8,690,968...8,702,213
Ensembl chrNW_004624786:8,690,461...8,702,771 		JBrowse link
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 acts_upstream_of_or_within ISO (PMID:12456676) MGI PMID:12456676 NCBI chrNW_004624742:10,845,333...10,883,705 JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) UniProt PMID:19523918 NCBI chrNW_004624908:531,313...549,570
Ensembl chrNW_004624908:531,308...549,990 		JBrowse link
positive regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (PMID:23767959) ParkinsonsUK-UCL PMID:23767959 NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834 		JBrowse link
regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:27806294) MGI PMID:27806294 NCBI chrNW_004624926:1,189,990...1,197,220
Ensembl chrNW_004624926:1,190,072...1,196,076 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      metabolic process 9450
        primary metabolic process 8379
          lipid metabolic process 1189
            phospholipid metabolic process 344
              glycerophospholipid metabolic process 267
                phosphatidic acid metabolic process 27
                  phosphatidic acid biosynthetic process + 23
paths to the root