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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of complement activation, classical pathway
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Accession:GO:0045959 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:exact_synonym: down regulation of complement activation, classical pathway;   downregulation of complement activation, classical pathway;   negative regulation of complement cascade, classical pathway
 narrow_synonym: inhibition of complement activation, classical pathway

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negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624870:2,082,050...2,096,220
Ensembl chrNW_004624870:2,081,968...2,099,517 		JBrowse link
G C4bpb complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624807:4,407,008...4,416,313
Ensembl chrNW_004624807:4,406,766...4,415,248 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G LOC101721321 C4b-binding protein alpha chain involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624807:4,371,116...4,403,425
Ensembl chrNW_004624807:4,370,969...4,401,458 		JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624835:5,531,507...5,600,181
Ensembl chrNW_004624835:5,531,472...5,599,922 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      immune effector process 553
        complement activation 46
          complement activation, classical pathway 23
            negative regulation of complement activation, classical pathway 5
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10620
      regulation of biological process 10303
        regulation of immune system process 1351
          negative regulation of immune system process 461
            negative regulation of immune effector process 110
              negative regulation of leukocyte mediated immunity 58
                negative regulation of lymphocyte mediated immunity 46
                  negative regulation of B cell mediated immunity 12
                    negative regulation of immunoglobulin mediated immune response 12
                      negative regulation of humoral immune response mediated by circulating immunoglobulin 8
                        negative regulation of complement activation, classical pathway 5
paths to the root