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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of natural killer cell mediated cytotoxicity
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Accession:GO:0045953 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
Synonyms:exact_synonym: down regulation of natural killer cell mediated cytotoxicity;   downregulation of natural killer cell mediated cytotoxicity;   negative regulation of NK cell mediated cell death;   negative regulation of NK cell mediated cell killing;   negative regulation of NK cell mediated cytotoxicity;   negative regulation of natural killer cell mediated cell death;   negative regulation of natural killer cell mediated cell killing
 narrow_synonym: inhibition of natural killer cell mediated cytotoxicity
 related_synonym: negative regulation of NK cell mediated cytolysis;   negative regulation of natural killer cell mediated cytolysis

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negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (PMID:18604210) UniProt PMID:18604210 NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914 		JBrowse link
G Clec12b C-type lectin domain family 12 member B involved_in ISO (PMID:17562706) UniProt PMID:17562706 NCBI chrNW_004624752:26,790,063...26,796,279 JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO RGD PMID:18835194 RGD:11568650 NCBI chrNW_004624786:4,153,783...4,177,611
Ensembl chrNW_004624786:4,153,889...4,177,716 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO RGD PMID:9021955 RGD:9685777 NCBI chrNW_004624913:273,126...276,353
Ensembl chrNW_004624913:273,705...275,693 		JBrowse link
G Igf2 insulin like growth factor 2 ISO RGD PMID:9021955 RGD:9685777 NCBI chrNW_004624767:14,969,977...14,997,577
Ensembl chrNW_004624767:14,969,866...14,979,026 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) UniProt PMID:23408620 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Sh2d1b SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:16127454) MGI PMID:16127454 NCBI chrNW_004624787:9,077,658...9,078,053 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) UniProt PMID:23408620 MGI:5491117 NCBI chrNW_004624786:478,048...491,086 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605 		JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chrNW_004624754:23,815,464...23,822,480
Ensembl chrNW_004624754:23,815,915...23,822,827 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chrNW_004624754:23,827,782...23,845,690
Ensembl chrNW_004624754:23,827,706...23,837,356 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      negative regulation of cellular process 4671
        negative regulation of cell killing 23
          negative regulation of leukocyte mediated cytotoxicity 17
            negative regulation of natural killer cell mediated cytotoxicity 11
              negative regulation of natural killer cell degranulation 1
              negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2
              protection from natural killer cell mediated cytotoxicity 2
Path 2
Term Annotations click to browse term
  biological_process 15093
    response to stimulus 8161
      response to external stimulus 2128
        response to external biotic stimulus 1317
          response to other organism 1314
            defense response to other organism 906
              defense response to symbiont 802
                innate immune response 664
                  natural killer cell mediated immunity 53
                    regulation of natural killer cell mediated immunity 32
                      negative regulation of natural killer cell mediated immunity 11
                        negative regulation of natural killer cell mediated cytotoxicity 11
                          negative regulation of natural killer cell degranulation 1
                          negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2
                          protection from natural killer cell mediated cytotoxicity 2
paths to the root