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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T-helper 1 cell differentiation
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Accession:GO:0045626 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of T-helper 1 cell differentiation;   downregulation of T-helper 1 cell differentiation
 narrow_synonym: inhibition of T-helper 1 cell differentiation
 related_synonym: negative regulation of T-helper 1 cell development

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negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) UniProt PMID:24463518 MGI:5565031 NCBI chrNW_004955422:14,051,140...14,053,521
Ensembl chrNW_004955422:14,051,140...14,053,521 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    immune system process 1980
      immune effector process 536
        negative regulation of immune effector process 116
          negative regulation of T-helper cell differentiation 19
            negative regulation of T-helper 1 cell differentiation 4
Path 2
Term Annotations click to browse term
  biological_process 12362
    cellular process 11484
      cellular developmental process 3880
        cell differentiation 3879
          cell development 2838
            hemopoiesis 920
              leukocyte differentiation 592
                mononuclear cell differentiation 483
                  lymphocyte differentiation 394
                    T cell differentiation 293
                      T cell differentiation involved in immune response 80
                        alpha-beta T cell differentiation involved in immune response 73
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 72
                            T-helper cell differentiation 70
                              regulation of T-helper cell differentiation 39
                                negative regulation of T-helper cell differentiation 19
                                  negative regulation of T-helper 1 cell differentiation 4
paths to the root