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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of B cell differentiation
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Accession:GO:0045578 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of B cell differentiation;   downregulation of B cell differentiation;   negative regulation of B lymphocyte differentiation
 narrow_synonym: inhibition of B cell differentiation
 related_synonym: negative regulation of B cell development


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negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) MGI PMID:16618805 NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,370,496...5,455,358 		JBrowse link
G HMGB3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) MGI PMID:12714519 NCBI chr  X:122,591,413...122,599,496
Ensembl chr  X:122,592,936...122,599,493 		JBrowse link
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:18523151) MGI PMID:18523151 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15240705) Ensembl
MGI		 PMID:15240705 GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 9:68,025,673...68,132,162 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18933
    immune system process 2575
      leukocyte activation 1051
        lymphocyte activation 863
          lymphocyte differentiation 448
            B cell differentiation 152
              negative regulation of B cell differentiation 6
                negative regulation of B-1 B cell differentiation 0
                negative regulation of central B cell anergy 0
                negative regulation of central B cell deletion 0
                negative regulation of plasma cell differentiation 2
Path 2
Term Annotations click to browse term
  biological_process 18933
    cellular process 18475
      cellular developmental process 4563
        cell differentiation 4562
          cell development 3239
            hemopoiesis 1042
              leukocyte differentiation 671
                mononuclear cell differentiation 545
                  lymphocyte differentiation 448
                    B cell differentiation 152
                      regulation of B cell differentiation 39
                        negative regulation of B cell differentiation 6
                          negative regulation of B-1 B cell differentiation 0
                          negative regulation of central B cell anergy 0
                          negative regulation of central B cell deletion 0
                          negative regulation of plasma cell differentiation 2
paths to the root