Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear pore central transport channel
go back to main search page
Accession:GO:0044613 term browser browse the term
Definition:The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
Synonyms:exact_synonym: nuclear pore central channel;   nuclear pore central plug;   nuclear pore transport channel
 related_synonym: karyopherin docking complex


show annotations for term's descendants           Sort by:
nuclear pore central transport channel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUP35 nucleoporin 35 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:88,587,753...88,616,310
Ensembl chr15:88,587,785...88,622,022 		JBrowse link
G NUP54 nucleoporin 54 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 8:71,792,153...71,833,180
Ensembl chr 8:71,792,155...71,833,157 		JBrowse link
G NUP62 nucleoporin 62 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:54,921,627...54,945,705
Ensembl chr 6:54,921,627...54,923,227 		JBrowse link
G NUTF2 nuclear transport factor 2 part_of ISO
IEA		 RGD
TreeGrafter		 PMID:10543952 GO_REF:0000118 RGD:9831376 NCBI chr 6:28,469,274...28,489,007
Ensembl chr 6:28,469,505...28,489,005 		JBrowse link
G NXT1 nuclear transport factor 2 like export factor 1 part_of IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:30,338,379...30,341,629
Ensembl chr17:30,338,391...30,341,628 		JBrowse link
G NXT2 nuclear transport factor 2 like export factor 2 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:89,684,733...89,691,808
Ensembl chr  X:89,684,671...89,691,805 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18687
    protein-containing complex 6005
      nuclear protein-containing complex 1244
        nuclear pore central transport channel 6
Path 2
Term Annotations click to browse term
  cellular_component 18687
    cellular anatomical entity 18466
      organelle 12444
        membrane-bounded organelle 11406
          intracellular membrane-bounded organelle 10861
            nucleus 6843
              nuclear protein-containing complex 1244
                nuclear pore 77
                  nuclear pore central transport channel 6
paths to the root