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cytolytic granule - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:cytolytic granule
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Accession:GO:0044194 term browser browse the term
Definition:A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.

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cytolytic granule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp1 lysosomal associated membrane protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:377,359...389,121
Ensembl chrNW_004936472:378,173...389,381 		JBrowse link
G Nkg7 natural killer cell granule protein 7 located_in ISO (PMID:32839608) UniProt PMID:32839608 NCBI chrNW_004937378:42,083...43,068
Ensembl chrNW_004937378:42,066...43,156 		JBrowse link
G Prf1 perforin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:8,057,874...8,060,695
Ensembl chrNW_004936521:8,057,874...8,060,695 		JBrowse link
G Rnf19b ring finger protein 19B located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:15,827,800...15,850,405
Ensembl chrNW_004936474:15,827,303...15,849,632 		JBrowse link
G Stxbp2 syntaxin binding protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,688,221...4,696,075
Ensembl chrNW_004936588:4,687,834...4,696,146 		JBrowse link
cytolytic granule membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ARF like GTPase 8B located_in IEA UniProt
Ensembl		 GO_REF:0000044 GO_REF:0000107 NCBI chrNW_004936577:4,430,939...4,475,186
Ensembl chrNW_004936577:4,430,898...4,475,212 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:377,359...389,121
Ensembl chrNW_004936472:378,173...389,381 		JBrowse link
G Nkg7 natural killer cell granule protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937378:42,083...43,068
Ensembl chrNW_004937378:42,066...43,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18224
    cellular anatomical structure 18002
      cytoplasm 10331
        vacuole 566
          lytic vacuole 465
            lysosome 465
              cytolytic granule 6
                cytolytic granule lumen 0
                cytolytic granule membrane 3
Path 2
Term Annotations click to browse term
  cellular_component 18224
    cellular anatomical structure 18002
      organelle 13281
        membrane-bounded organelle 12200
          intracellular membrane-bounded organelle 11665
            vacuole 566
              lytic vacuole 465
                lysosome 465
                  cytolytic granule 6
                    cytolytic granule lumen 0
                    cytolytic granule membrane 3
paths to the root