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ONTOLOGY REPORT - ANNOTATIONS

Term:cytotoxic T cell degranulation
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Accession:GO:0043316 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
Synonyms:exact_synonym: cytotoxic T cell granule exocytosis;   cytotoxic T lymphocyte degranulation;   cytotoxic T lymphocyte granule exocytosis

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cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:11266473) MGI PMID:11266473 NCBI chrNW_004624731:6,315,064...6,355,431
Ensembl chrNW_004624731:6,319,092...6,355,534 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO (PMID:23042080), (PMID:23190531) MGI PMID:23042080 PMID:23190531 NCBI chrNW_004624753:10,150,811...10,180,794
Ensembl chrNW_004624753:10,148,416...10,191,153 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      immune effector process 553
        leukocyte degranulation 80
          cytotoxic T cell degranulation 3
            negative regulation of cytotoxic T cell degranulation 1
            positive regulation of cytotoxic T cell degranulation 0
            regulation of cytotoxic T cell degranulation + 1
Path 2
Term Annotations click to browse term
  biological_process 15093
    localization 4970
      establishment of localization 4307
        transport 4014
          export from cell 988
            secretion by cell 923
              exocytosis 360
                regulated exocytosis 251
                  leukocyte degranulation 80
                    cytotoxic T cell degranulation 3
                      negative regulation of cytotoxic T cell degranulation 1
                      positive regulation of cytotoxic T cell degranulation 0
                      regulation of cytotoxic T cell degranulation + 1
paths to the root