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bile acid nuclear receptor activity - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:bile acid nuclear receptor activity
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Accession:GO:0038186 term browser browse the term
Definition:A nuclear receptor activity regulated by a bile acid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.
Synonyms:related_synonym: farnesoid X nuclear receptor activity;   farnesoid X receptor activity;   lithocholic acid receptor activity
 xref: Reactome:R-HSA-5340195 "NR1H4 binds DCA, CDCA, LCHA"

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bile acid nuclear receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 enables ISO PMID:12718893
(PMID:10334992), (PMID:21757002), (PMID:23767959)
(PMID:21757002) 		UniProt
ParkinsonsUK-UCL
BHF-UCL		 PMID:10334992 PMID:12718893 PMID:21757002 PMID:23767959 RGD:15090836 RGD:1625198 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751 		JBrowse link
G Vdr vitamin D receptor enables ISO (PMID:12016314), (PMID:32354638) UniProt PMID:12016314 PMID:32354638 NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14394
    molecular transducer activity 667
      signaling receptor activity 667
        nuclear receptor activity 37
          bile acid nuclear receptor activity 2
Path 2
Term Annotations click to browse term
  molecular_function 14394
    transcription regulator activity 1069
      DNA-binding transcription factor activity 721
        DNA-binding transcription factor activity, RNA polymerase II-specific 678
          nuclear receptor activity 37
            bile acid nuclear receptor activity 2
paths to the root