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ONTOLOGY REPORT - ANNOTATIONS

Term:somatostatin receptor signaling pathway
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Accession:GO:0038169 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Comment:In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.
Synonyms:exact_synonym: SST receptor signaling pathway
 related_synonym: SSTR signaling pathway


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somatostatin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SST somatostatin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:184,695,561...184,697,091
Ensembl chr 3:193,155,363...193,158,337 		JBrowse link
G SSTR1 somatostatin receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr14:18,968,969...18,973,560
Ensembl chr14:37,329,309...37,330,484 		JBrowse link
G SSTR2 somatostatin receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr17:67,093,013...67,099,086
Ensembl chr17:72,553,506...72,554,615 		JBrowse link
G SSTR3 somatostatin receptor 3 involved_in IEA GOC GO_REF:0000108 NCBI chr22:18,116,993...18,125,170
Ensembl chr22:35,954,232...35,955,488 		JBrowse link
G SSTR4 somatostatin receptor 4 involved_in IEA GOC GO_REF:0000108 NCBI chr20:22,982,009...22,986,058
Ensembl chr20:23,333,320...23,334,766 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16641
    cellular process 16198
      signal transduction 5469
        G protein-coupled receptor signaling pathway 1133
          somatostatin receptor signaling pathway 5
            somatostatin signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 16641
    biological regulation 11630
      regulation of biological process 11253
        signaling 5969
          signal transduction 5469
            G protein-coupled receptor signaling pathway 1133
              somatostatin receptor signaling pathway 5
                somatostatin signaling pathway 5
paths to the root