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ONTOLOGY REPORT - ANNOTATIONS


Term:intraciliary retrograde transport
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Accession:GO:0035721 term browser browse the term
Definition:The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
Comment:Note that we deem cilium and microtubule-based flagellum to be equivalent.
Synonyms:exact_synonym: intraflagellar retrograde transport


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intraciliary retrograde transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CILK1 ciliogenesis associated kinase 1 involved_in ISO (MGI:5787768|PMID:25243405) UniProt PMID:25243405 MGI:5787768 NCBI chr17:19,509,955...19,572,011
Ensembl chr17:19,510,106...19,572,002
JBrowse link
G DYNC2H1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18488998) Ensembl
MGI
PMID:18488998 GO_REF:0000107 NCBI chr 1:94,484,090...94,849,960
Ensembl chr 1:94,484,512...94,849,581
JBrowse link
G DYNC2I1 dynein 2 intermediate chain 1 involved_in ISO (PMID:29742051), (PMID:30649997) UniProt PMID:29742051 PMID:30649997 NCBI chr21:126,798,952...126,828,361 JBrowse link
G DYNC2I2 dynein 2 intermediate chain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,470,588...9,503,754
Ensembl chr12:9,479,403...9,503,671
JBrowse link
G DYNC2LI1 dynein cytoplasmic 2 light intermediate chain 1 involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr14:63,441,948...63,481,460
Ensembl chr14:63,440,155...63,481,479
JBrowse link
G DYNLL1 dynein light chain LC8-type 1 acts_upstream_of_or_within ISO (PMID:25294941) MGI PMID:25294941 NCBI chr11:115,851,020...115,855,526
Ensembl chr11:115,851,381...115,851,647
JBrowse link
G DYNLT2B dynein light chain Tctex-type 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:90,867,250...90,902,064
Ensembl chr15:90,867,322...90,902,667
JBrowse link
G IFT122 intraflagellar transport 122 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:51,528,383...51,616,757
Ensembl chr22:51,528,254...51,616,682
JBrowse link
G IFT140 intraflagellar transport 140 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24009529) TreeGrafter
MGI
PMID:24009529 GO_REF:0000118 NCBI chr 5:1,419,432...1,523,342
Ensembl chr 5:1,415,664...1,521,843
JBrowse link
G IFT43 intraflagellar transport 43 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr24:53,231,293...53,329,116
Ensembl chr24:53,231,300...53,329,109
JBrowse link
G LOC103227169 dynein light chain 1, cytoplasmic involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:116,951,646...116,952,307
Ensembl chr11:115,851,381...115,851,647
JBrowse link
G TTC21A tetratricopeptide repeat domain 21A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:276,965...308,194
Ensembl chr15:277,078...308,194
JBrowse link
G TTC21B tetratricopeptide repeat domain 21B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19732765)
(PMID:18327258)
(PMID:27482817)
Ensembl
MGI
TreeGrafter
PMID:18327258 PMID:19732765 PMID:27482817 GO_REF:0000107 GO_REF:0000118 NCBI chr10:51,365,156...51,449,207
Ensembl chr10:51,364,889...51,449,183
JBrowse link
G WDR19 WD repeat domain 19 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:20889716) MGI
TreeGrafter
Ensembl
InterPro
PMID:20889716 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr27:11,019,897...11,113,760
Ensembl chr27:11,018,827...11,113,666
JBrowse link
G WDR35 WD repeat domain 35 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:20889716) MGI
TreeGrafter
Ensembl
UniProt
PMID:20889716 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr14:87,732,034...87,801,687
Ensembl chr14:87,732,049...87,801,852
JBrowse link
regulation of intraciliary retrograde transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNLT2B dynein light chain Tctex-type 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:90,867,250...90,902,064
Ensembl chr15:90,867,322...90,902,667
JBrowse link
G TTC21B tetratricopeptide repeat domain 21B involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:51,365,156...51,449,207
Ensembl chr10:51,364,889...51,449,183
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    localization 5384
      protein-containing complex localization 279
        intraciliary transport 42
          intraciliary retrograde transport 15
            negative regulation of intraciliary retrograde transport 0
            positive regulation of intraciliary retrograde transport 0
            regulation of intraciliary retrograde transport + 2
Path 2
Term Annotations click to browse term
  biological_process 16925
    cellular process 15870
      cellular localization 3551
        establishment of localization in cell 2088
          intracellular transport 1343
            cytoskeleton-dependent intracellular transport 204
              transport along microtubule 175
                intraciliary transport 42
                  intraciliary retrograde transport 15
                    negative regulation of intraciliary retrograde transport 0
                    positive regulation of intraciliary retrograde transport 0
                    regulation of intraciliary retrograde transport + 2
paths to the root