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ONTOLOGY REPORT - ANNOTATIONS

Term:PR-DUB complex
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Accession:GO:0035517 term browser browse the term
Definition:A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.
Synonyms:exact_synonym: Polycomb repressive deubiquitinase complex


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PR-DUB complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl1 ASXL transcriptional regulator 1 part_of ISO
IBA		 (PMID:20436459)
GO_REF:0000033		 RGD
GO_Central		 PMID:20436459 GO_REF:0000033 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Asxl3 ASXL transcriptional regulator 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:13,593,529...13,766,324
Ensembl chr18:13,593,985...13,762,427 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 part_of ISO
IEA
ISS		 (PMID:20436459), (PMID:25451922)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20436459 PMID:25451922 GO_REF:0000024 GO_REF:0000107 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    protein-containing complex 6790
      nuclear protein-containing complex 1338
        PcG protein complex 53
          PR-DUB complex 4
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      organelle 14240
        membrane-bounded organelle 12805
          intracellular membrane-bounded organelle 12253
            nucleus 7647
              nuclear protein-containing complex 1338
                PcG protein complex 53
                  PR-DUB complex 4
paths to the root