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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208

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histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chrNW_004936552:3,921,217...3,964,281
Ensembl chrNW_004936552:3,921,490...3,962,648 		JBrowse link
G Kdm5a lysine demethylase 5A enables IEA UniProt
Ensembl
TreeGrafter		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936606:486,424...570,546
Ensembl chrNW_004936606:485,655...570,739 		JBrowse link
G Kdm5b lysine demethylase 5B enables IEA TreeGrafter
UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936567:1,782,056...1,860,861
Ensembl chrNW_004936567:1,781,995...1,863,461 		JBrowse link
G Kdm5c lysine demethylase 5C enables IEA UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004936751:159,628...204,136
Ensembl chrNW_004936751:167,920...203,966 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:2,766,406...2,768,551
Ensembl chrNW_004936488:2,766,451...2,768,408 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17128
    catalytic activity 5252
      oxidoreductase activity 692
        dioxygenase activity 95
          2-oxoglutarate-dependent dioxygenase activity 58
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 17128
    catalytic activity 5252
      demethylase activity 36
        protein demethylase activity 26
          histone demethylase activity 26
            histone H3 demethylase activity 24
              histone H3K4 demethylase activity 7
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
paths to the root