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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4 demethylase activity
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Accession:GO:0032453 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein.
Synonyms:exact_synonym: histone H3-K4 demethylase activity;   histone H3-methyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4 specific);   histone demethylase activity (H3K4-specific)
 xref: Reactome:R-HSA-9822461 "KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3)";   Reactome:R-HSA-9822467 "KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3)"



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histone H3K4 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO (PMID:24217620)
(PMID:15620353), (PMID:24217620), (PMID:27292636)
RGD PMID:15620353 PMID:24217620 PMID:27292636 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm1b lysine demethylase 1B enables ISO (PMID:19407342), (PMID:19727073) RGD PMID:19407342 PMID:19727073 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
G Kdm5a lysine demethylase 5A enables ISO (PMID:18483221) RGD PMID:18483221 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kdm5b lysine demethylase 5B enables ISO (PMID:18048344), (PMID:24952722), (PMID:27214403), (PMID:28262558)
(PMID:17320160)
RGD PMID:17320160 PMID:18048344 PMID:24952722 PMID:27214403 PMID:28262558 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdm5c lysine demethylase 5C enables ISO (PMID:17320160), (PMID:18078810), (PMID:28262558)
(PMID:23246292)
RGD PMID:17320160 PMID:18078810 PMID:23246292 PMID:28262558 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870
JBrowse link
G Kdm5d lysine demethylase 5D enables ISO (PMID:17320160) RGD PMID:17320160 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018
JBrowse link
G Riox1 ribosomal oxygenase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250
JBrowse link
G Riox2 ribosomal oxygenase 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574
JBrowse link
FAD-dependent H3K4me/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO
IBA
(PMID:24843136)
(PMID:20228790), (PMID:27292636)
GO_REF:0000033
RGD
GO_Central
PMID:20228790 PMID:24843136 PMID:27292636 GO_REF:0000033 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm1b lysine demethylase 1B enables ISO (PMID:23260659), (PMID:23266887), (PMID:23357850)
(PMID:19407342), (PMID:19727073)
(PMID:30970244)
RGD PMID:19407342 PMID:19727073 PMID:23260659 PMID:23266887 PMID:23357850 More... NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) RGD PMID:19407342 PMID:19727073 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
G Kdm5a lysine demethylase 5A enables ISO
IBA
(PMID:18270511)
GO_REF:0000033
RGD
GO_Central
PMID:18270511 GO_REF:0000033 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
IBA
(PMID:20228790), (PMID:20403335)
GO_REF:0000033
RGD
GO_Central
PMID:20228790 PMID:20403335 GO_REF:0000033 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdm5c lysine demethylase 5C enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870
JBrowse link
G Kdm5d lysine demethylase 5D enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018
JBrowse link
G Riox1 ribosomal oxygenase 1 enables ISO (PMID:19927124) RGD PMID:19927124 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21088
    catalytic activity 6122
      demethylase activity 42
        protein demethylase activity 30
          histone demethylase activity 30
            histone H3 demethylase activity 26
              histone H3K4 demethylase activity 8
                FAD-dependent H3K4me/H3K4me3 demethylase activity 2
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
paths to the root