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ONTOLOGY REPORT - ANNOTATIONS

Term:iron import into cell
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Accession:GO:0033212 term browser browse the term
Definition:The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
Synonyms:narrow_synonym: ferrous ion import;   ferrous iron import;   ferrous iron uptake
 related_synonym: iron assimilation
 alt_id: GO:0070627

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iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC11A2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11739192) Ensembl
MGI		 PMID:11739192 GO_REF:0000107 NCBI chr11:47,190,138...47,238,543
Ensembl chr11:47,197,168...47,235,130 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781) UniProt PMID:20682781 NCBI chr 8:20,446,756...20,502,585 JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 8:20,491,284...20,502,626 JBrowse link
G STEAP3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chr10:11,055,446...11,097,131
Ensembl chr10:11,053,981...11,075,452 		JBrowse link
G STEAP4 STEAP4 metalloreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16609065) Ensembl
MGI		 PMID:16609065 GO_REF:0000107 NCBI chr21:60,653,504...60,680,414
Ensembl chr21:60,653,454...60,680,323 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFR2 transferrin receptor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:12,570,604...12,592,269
Ensembl chr28:12,571,841...12,592,266 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC39A8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:50,355,756...50,451,253
Ensembl chr 7:50,367,436...50,451,510 		JBrowse link
G STEAP2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chr21:58,689,298...58,718,386 JBrowse link
G STEAP2 STEAP2 metalloreductase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:58,701,578...58,718,290 JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,753,175...103,760,168
Ensembl chr11:103,753,189...103,760,364 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr12:9,976,278...9,981,087
Ensembl chr12:9,976,614...9,980,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17021
    localization 5392
      establishment of localization 4704
        establishment of localization in cell 2061
          iron import into cell 12
            endocytic iron import into cell + 1
            heme import into cell + 0
            iron ion import across plasma membrane + 6
            reductive iron assimilation 0
            siderophore-dependent iron import into cell + 0
Path 2
Term Annotations click to browse term
  biological_process 17021
    localization 5392
      establishment of localization 4704
        transport 4402
          monoatomic ion transport 1278
            monoatomic cation transport 1085
              metal ion transport 921
                transition metal ion transport 107
                  iron ion transport 61
                    iron import into cell 12
                      endocytic iron import into cell + 1
                      heme import into cell + 0
                      iron ion import across plasma membrane + 6
                      reductive iron assimilation 0
                      siderophore-dependent iron import into cell + 0
paths to the root