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purine-rich negative regulatory element binding - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS


Term:purine-rich negative regulatory element binding
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Accession:GO:0032422 term browser browse the term
Definition:Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
Synonyms:broad_synonym: PNR element binding


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purine-rich negative regulatory element binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELK3 ETS transcription factor ELK3 enables IDA (PMID:12933792) HGNC-UCL PMID:12933792 NCBI chr12:96,194,375...96,269,824
Ensembl chr12:96,194,375...96,269,824
JBrowse link
G PURA purine rich element binding protein A enables IEA
ISS
IBA
Ensembl
BHF-UCL
GO_Central
InterPro
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619
JBrowse link
G PURB purine rich element binding protein B enables IEA
IBA
ISS
InterPro
GO_Central
BHF-UCL
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:44,876,299...44,885,530
Ensembl chr 7:44,876,299...44,885,530
JBrowse link
G PURG purine rich element binding protein G enables IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr 8:30,995,802...31,033,356
Ensembl chr 8:30,995,802...31,033,715
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19542
    binding 18020
      nucleic acid binding 4629
        transcription regulatory region nucleic acid binding 1499
          transcription cis-regulatory region binding 1494
            purine-rich negative regulatory element binding 4
Path 2
Term Annotations click to browse term
  molecular_function 19542
    binding 18020
      nucleic acid binding 4629
        DNA binding 2655
          double-stranded DNA binding 1677
            sequence-specific double-stranded DNA binding 1570
              transcription cis-regulatory region binding 1494
                purine-rich negative regulatory element binding 4
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