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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of actin filament depolymerization
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Accession:GO:0030836 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin depolymerization.
Comment:Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838').
Synonyms:exact_synonym: actin filament destabilization;   positive regulation of actin depolymerization;   up regulation of actin filament depolymerization;   upregulation of actin filament depolymerization
 narrow_synonym: activation of actin filament depolymerization;   stimulation of actin filament depolymerization
 broad_synonym: positive regulation of actin polymerization and/or depolymerization
 alt_id: GO:0030045

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positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:15548599)
(PMID:23921380)		 MGI
CACAO		 PMID:15548599 PMID:23921380 NCBI chrNW_004624767:20,574,884...20,578,413
Ensembl chrNW_004624767:20,574,966...20,579,796 		JBrowse link
G Cfl2 cofilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624838:2,032,658...2,036,893
Ensembl chrNW_004624838:2,031,895...2,037,728 		JBrowse link
G Dstn destrin, actin depolymerizing factor acts_upstream_of_or_within ISO (PMID:15548599) MGI PMID:15548599 NCBI chrNW_004624741:18,728,734...18,758,281
Ensembl chrNW_004624741:18,728,705...18,759,094 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17500066) UniProt PMID:17500066 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO (PMID:15580268) UniProt PMID:15580268 NCBI chrNW_004624752:10,244,424...10,251,072
Ensembl chrNW_004624752:10,243,135...10,251,082 		JBrowse link
G Plek pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:4,939,683...4,967,327
Ensembl chrNW_004624762:4,939,599...4,967,371 		JBrowse link
G Sema5a semaphorin 5A involved_in ISO (PMID:19850054) UniProt PMID:19850054 NCBI chrNW_004624751:6,429,814...6,913,673
Ensembl chrNW_004624751:6,436,854...6,738,216 		JBrowse link
G Vil1 villin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:6,567,107...6,593,258
Ensembl chrNW_004624823:6,566,687...6,588,599 		JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (PMID:24840128) MGI PMID:24840128 NCBI chrNW_004624755:21,090,599...21,124,107
Ensembl chrNW_004624755:21,090,717...21,123,259 		JBrowse link
actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) UniProt PMID:25433700 NCBI chrNW_004624775:13,917,215...13,989,093
Ensembl chrNW_004624775:13,916,883...13,989,153 		JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) UniProt PMID:16054028 NCBI chrNW_004624756:1,446,633...1,751,043
Ensembl chrNW_004624756:1,446,200...1,751,211 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) UniProt PMID:16054028 NCBI chrNW_004624756:1,446,633...1,751,043
Ensembl chrNW_004624756:1,446,200...1,751,211 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chrNW_004624746:18,692,179...18,704,952
Ensembl chrNW_004624746:18,692,225...18,704,476 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chrNW_004624761:13,065,318...13,367,504 JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chrNW_004624966:436,196...500,275 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      positive regulation of cellular process 5668
        positive regulation of cellular component organization 1226
          positive regulation of supramolecular fiber organization 179
            positive regulation of actin filament depolymerization 14
              actin filament uncapping + 2
              negative regulation of barbed-end actin filament capping 4
Path 2
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      cellular component organization or biogenesis 6274
        cellular component organization 6087
          organelle organization 3337
            cytoskeleton organization 1376
              actin cytoskeleton organization 661
                actin filament organization 420
                  actin polymerization or depolymerization 184
                    regulation of actin polymerization or depolymerization 152
                      regulation of actin filament depolymerization 56
                        positive regulation of actin filament depolymerization 14
                          actin filament uncapping + 2
                          negative regulation of barbed-end actin filament capping 4
paths to the root