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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear estrogen receptor activity
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Accession:GO:0030284 term browser browse the term
Definition:A nuclear receptor activity regulated by estrogen binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.
Synonyms:broad_synonym: estrogen receptor activity


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nuclear estrogen receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G ESR2 estrogen receptor 2 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 enables ISO (PMID:15539556), (PMID:15705806)
(PMID:23545157)		 UniProt PMID:15539556 PMID:15705806 PMID:23545157 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G PDE3A phosphodiesterase 3A enables IEA Ensembl GO_REF:0000107 NCBI chr12:20,380,213...20,690,540
Ensembl chr12:20,763,999...21,064,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17686
    molecular transducer activity 1275
      signaling receptor activity 1275
        nuclear receptor activity 50
          nuclear steroid receptor activity 19
            nuclear estrogen receptor activity 4
Path 2
Term Annotations click to browse term
  molecular_function 17686
    transcription regulator activity 1663
      DNA-binding transcription factor activity 1242
        DNA-binding transcription factor activity, RNA polymerase II-specific 1160
          nuclear receptor activity 50
            nuclear steroid receptor activity 19
              nuclear estrogen receptor activity 4
paths to the root