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ONTOLOGY REPORT - ANNOTATIONS

Term:potassium:chloride symporter activity
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Accession:GO:0015379 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).
Synonyms:broad_synonym: potassium ion symporter activity
 alt_id: GO:0022820
 xref: RHEA:72427;   Reactome:R-HSA-5623806 "Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region";   TC:2.A.30.1.5;   reactome:R-HSA-426155 "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region"


show annotations for term's descendants           Sort by:
potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC12A4 solute carrier family 12 member 4 enables IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:28,554,162...28,576,458
Ensembl chr 6:28,553,616...28,576,504 		JBrowse link
G SLC12A5 solute carrier family 12 member 5 enables ISO
IEA
IBA		 RGD
Ensembl
InterPro
GO_Central		 PMID:9374636 PMID:10942735 PMID:12040048 PMID:15175220 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:2303818 RGD:2303821 RGD:2303952 RGD:628350 NCBI chr17:48,192,072...48,230,674
Ensembl chr17:48,192,075...48,230,661 		JBrowse link
G SLC12A6 solute carrier family 12 member 6 enables IEA
IBA		 Ensembl
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:80,164,788...80,266,335
Ensembl chr 7:80,164,911...80,268,323 		JBrowse link
G SLC12A7 solute carrier family 12 member 7 enables IEA
IBA		 Ensembl
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:79,356,868...79,396,652
Ensembl chr16:79,357,010...79,396,656 		JBrowse link
G SLC12A8 solute carrier family 12 member 8 enables IBA GO_Central GO_REF:0000033 NCBI chr13:135,105,723...135,249,124
Ensembl chr13:135,105,896...135,249,120 		JBrowse link
G SLC12A9 solute carrier family 12 member 9 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:8,696,593...8,712,904
Ensembl chr 3:8,697,439...8,712,918 		JBrowse link
sodium:potassium:chloride symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC12A1 solute carrier family 12 member 1 enables ISO
IEA
IBA		 RGD
UniProt
GO_Central
Ensembl		 PMID:16291577 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 RGD:1624189 NCBI chr 1:123,481,892...123,571,655
Ensembl chr 1:123,481,369...123,571,630 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 enables ISO
IEA
IBA		 RGD
UniProt
GO_Central
Ensembl		 PMID:12556450 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 RGD:1580435 NCBI chr 2:131,016,430...131,109,307
Ensembl chr 2:131,016,418...131,109,299 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:18,844,752...18,885,497
Ensembl chr 6:18,844,600...18,885,476 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19428
    transporter activity 1219
      transmembrane transporter activity 1112
        monoatomic ion transmembrane transporter activity 730
          monoatomic cation transmembrane transporter activity 611
            metal ion transmembrane transporter activity 444
              potassium ion transmembrane transporter activity 166
                potassium:chloride symporter activity 9
                  sodium:potassium:chloride symporter activity 3
Path 2
Term Annotations click to browse term
  molecular_function 19428
    transporter activity 1219
      transmembrane transporter activity 1112
        active transmembrane transporter activity 415
          secondary active transmembrane transporter activity 264
            symporter activity 135
              solute:monoatomic cation symporter activity 111
                monoatomic anion:monoatomic cation symporter activity 27
                  chloride:monoatomic cation symporter activity 23
                    potassium:chloride symporter activity 9
                      sodium:potassium:chloride symporter activity 3
paths to the root