SLC12A2 (solute carrier family 12 member 2) - Rat Genome Database
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Gene: SLC12A2 (solute carrier family 12 member 2) Sus scrofa
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Symbol: SLC12A2
Name: solute carrier family 12 member 2
RGD ID: 14174717
Description: ENCODES a protein that exhibits metal ion transmembrane transporter activity (ortholog); potassium ion transmembrane transporter activity (ortholog); INVOLVED IN aging (ortholog); branching involved in mammary gland duct morphogenesis (ortholog); cellular chloride ion homeostasis (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); autosomal dominant nonsyndromic deafness 78 (ortholog); carcinoma (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell body (ortholog); cell periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: solute carrier family 12 (sodium/potassium/chloride transporters), member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2131,016,430 - 131,109,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12131,016,430 - 131,109,307 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22136,368,254 - 136,460,658 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

Genomics

Comparative Map Data
SLC12A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2131,016,430 - 131,109,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12131,016,430 - 131,109,307 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22136,368,254 - 136,460,658 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC12A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5128,083,766 - 128,189,677 (+)EnsemblGRCh38hg38GRCh38
GRCh385128,083,766 - 128,189,677 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375127,419,483 - 127,525,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365127,447,382 - 127,553,279 (+)NCBINCBI36hg18NCBI36
Build 345127,447,381 - 127,553,278NCBI
Celera5123,551,492 - 123,657,387 (+)NCBI
Cytogenetic Map5q23.3NCBI
HuRef5122,610,291 - 122,716,113 (+)NCBIHuRef
CHM1_15126,852,070 - 126,957,950 (+)NCBICHM1_1
Slc12a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391858,011,505 - 58,079,893 (+)NCBIGRCm39mm39
GRCm381857,878,512 - 57,946,821 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,878,678 - 57,946,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv371858,038,332 - 58,106,475 (+)NCBIGRCm37mm9NCBIm37
MGSCv361858,004,047 - 58,072,174 (+)NCBImm8
Celera1859,157,060 - 59,258,313 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1832.15NCBI
Slc12a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01852,917,124 - 52,985,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1852,917,124 - 52,985,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01852,104,434 - 52,172,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41853,673,215 - 53,741,352 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11853,735,140 - 53,805,295 (+)NCBI
Celera1849,478,614 - 49,546,320 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Slc12a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554151,137,327 - 1,219,241 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554151,138,297 - 1,219,241 (+)NCBIChiLan1.0ChiLan1.0
SLC12A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15129,260,476 - 129,364,563 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5129,262,134 - 129,364,563 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05123,499,267 - 123,603,777 (+)NCBIMhudiblu_PPA_v0panPan3
SLC12A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1117,143,943 - 17,253,695 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11117,143,943 - 17,256,248 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc12a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365041,378,812 - 1,465,463 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC12A2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12331,028,514 - 31,132,263 (+)NCBI
ChlSab1.1 Ensembl2331,029,026 - 31,132,289 (+)Ensembl
Slc12a2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477413,236,306 - 13,335,412 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 1 1 2 19 2 1
Low 4 2 4 4 2 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015576   ⟹   ENSSSCP00000015164
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2131,016,591 - 131,109,301 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000059173   ⟹   ENSSSCP00000042341
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2131,016,430 - 131,109,301 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062062   ⟹   ENSSSCP00000049931
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2131,016,617 - 131,109,301 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000068217   ⟹   ENSSSCP00000062947
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2131,016,430 - 131,104,601 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000090879   ⟹   ENSSSCP00000069914
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2131,016,430 - 131,109,305 (+)Ensembl
RefSeq Acc Id: XM_003123899   ⟹   XP_003123947
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12131,016,430 - 131,109,307 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005661615   ⟹   XP_005661672
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12131,016,443 - 131,109,307 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003123947 (Get FASTA)   NCBI Sequence Viewer  
  XP_005661672 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003123947   ⟸   XM_003123899
- Peptide Label: isoform X1
- UniProtKB: A0A287AEN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005661672   ⟸   XM_005661615
- Peptide Label: isoform X2
- UniProtKB: F1RKK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015164   ⟸   ENSSSCT00000015576
RefSeq Acc Id: ENSSSCP00000062947   ⟸   ENSSSCT00000068217
RefSeq Acc Id: ENSSSCP00000069914   ⟸   ENSSSCT00000090879
RefSeq Acc Id: ENSSSCP00000042341   ⟸   ENSSSCT00000059173
RefSeq Acc Id: ENSSSCP00000049931   ⟸   ENSSSCT00000062062
Protein Domains
AA_permease   AA_permease_N   SLC12


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014255 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000015164 UniProtKB/TrEMBL
  ENSSSCP00000042341 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000049931 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000062947 UniProtKB/TrEMBL
  ENSSSCP00000069914 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015576 UniProtKB/TrEMBL
  ENSSSCT00000059173 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000062062 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000068217 UniProtKB/TrEMBL
  ENSSSCT00000090879 UniProtKB/TrEMBL
InterPro AA-permease/SLC12A_dom UniProtKB/TrEMBL
  AA_permease_N UniProtKB/TrEMBL
  Na/K/Cl_cotranspt UniProtKB/TrEMBL
  NKCC1 UniProtKB/TrEMBL
  SLC12_C UniProtKB/TrEMBL
  SLC12A_fam UniProtKB/TrEMBL
KEGG Report ssc:100516960 UniProtKB/TrEMBL
NCBI Gene SLC12A2 ENTREZGENE
PANTHER PTHR11827:SF58 UniProtKB/TrEMBL
Pfam AA_permease UniProtKB/TrEMBL
  AA_permease_N UniProtKB/TrEMBL
  SLC12 UniProtKB/TrEMBL
PRINTS NAKCLTRNSPRT UniProtKB/TrEMBL
  NAKCLTRSPRT1 UniProtKB/TrEMBL
TIGRFAMs 2a30 UniProtKB/TrEMBL
UniGene Ssc.45258 ENTREZGENE
UniProt A0A287AEN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B1F9_PIG UniProtKB/TrEMBL
  A0A480HW11_PIG UniProtKB/TrEMBL
  A0A5G2QXK9_PIG UniProtKB/TrEMBL
  A0A5G2RFR6_PIG UniProtKB/TrEMBL
  F1RKK2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92922 ENTREZGENE