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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of microtubule nucleation
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Accession:GO:0010968 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.


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regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EML2 EMAP like 2 involved_in ISO (PMID:11694528) UniProt PMID:11694528 NCBI chr19:42,614,590...42,652,956
Ensembl chr19:51,153,241...51,191,754 		JBrowse link
G NME7 NME/NM23 family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:144,620,719...144,850,230
Ensembl chr 1:148,343,026...148,572,499 		JBrowse link
negative regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:27012601) UniProt PMID:27012601 NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413 		JBrowse link
positive regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CKAP5 cytoskeleton associated protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,694,967...46,797,500
Ensembl chr11:47,252,752...47,329,274 		JBrowse link
G DCTN1 dynactin subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,428,060...74,458,574
Ensembl chr2A:75,934,752...75,953,296 		JBrowse link
G GIT1 GIT ArfGAP 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:27137183) UniProt PMID:27137183 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:27137183) UniProt PMID:27137183 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G LOC100988482 myomegalin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:120,522,499...120,693,837 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19380
    cellular process 18938
      microtubule-based process 1035
        microtubule cytoskeleton organization 668
          microtubule nucleation 38
            regulation of microtubule nucleation 11
              negative regulation of microtubule nucleation 1
              positive regulation of microtubule nucleation + 8
Path 2
Term Annotations click to browse term
  biological_process 19380
    cellular process 18938
      cellular component organization or biogenesis 8455
        cellular component organization 8253
          organelle organization 3502
            regulation of organelle organization 1172
              regulation of cytoskeleton organization 531
                regulation of microtubule cytoskeleton organization 166
                  regulation of microtubule polymerization or depolymerization 96
                    regulation of microtubule polymerization 60
                      regulation of microtubule nucleation 11
                        negative regulation of microtubule nucleation 1
                        positive regulation of microtubule nucleation + 8
paths to the root