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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA methyltransferase activity
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Accession:GO:0008174 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.


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mRNA methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL8 methyltransferase 8, tRNA N3-cytidine enables
NOT|enables		 IEA
ISO		 (PMID:34774131) Ensembl
UniProt		 PMID:34774131 GO_REF:0000107 NCBI chr36:15,816,518...15,906,019
Ensembl chr36:15,819,138...15,905,064 		JBrowse link
internal mRNA (guanine-N7-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL1 methyltransferase 1, tRNA methylguanosine enables ISO (PMID:31031084), (PMID:37379838) UniProt PMID:31031084 PMID:37379838 NCBI chr10:1,831,088...1,833,818
Ensembl chr10:1,831,091...1,833,868 		JBrowse link
mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCIF1 phosphorylated CTD interacting factor 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr24:33,214,370...33,225,922
Ensembl chr24:33,214,419...33,226,732 		JBrowse link
mRNA (adenine-N1-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRMT61A tRNA methyltransferase 61A enables IEA Ensembl GO_REF:0000107 NCBI chr 8:71,294,129...71,300,679
Ensembl chr 8:71,294,303...71,300,687 		JBrowse link
G TRMT61B tRNA methyltransferase 61B enables ISO (PMID:29107537) UniProt PMID:29107537 NCBI chr17:22,742,380...22,757,362
Ensembl chr17:22,742,175...22,757,349 		JBrowse link
mRNA (cytidine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NSUN2 NOP2/Sun RNA methyltransferase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr34:7,145,176...7,172,761
Ensembl chr34:7,144,586...7,172,335 		JBrowse link
G NSUN4 NOP2/Sun RNA methyltransferase 4 enables ISO (PMID:39019044) UniProt PMID:39019044 NCBI chr15:14,054,061...14,069,080
Ensembl chr15:14,056,004...14,068,190 		JBrowse link
mRNA (nucleoside-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMTR1 cap methyltransferase 1 enables IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000117 NCBI chr12:6,454,605...6,505,127
Ensembl chr12:6,454,652...6,504,776 		JBrowse link
G CMTR2 cap methyltransferase 2 enables IEA
IBA		 Ensembl
GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:77,117,795...77,124,995
Ensembl chr 5:77,118,964...77,121,264 		JBrowse link
G RNF8 ring finger protein 8 enables IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000117 NCBI chr12:6,380,365...6,415,407
Ensembl chr12:6,292,459...6,415,382 		JBrowse link
mRNA 5'-cap (guanine-N7-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNMT RNA guanine-7 methyltransferase enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:24,465,634...24,499,526
Ensembl chr 1:24,430,063...24,497,206 		JBrowse link
mRNA m(6)A methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit enables
NOT|enables		 IEA
ISO		 (PMID:27627798) Ensembl
UniProt		 PMID:27627798 GO_REF:0000107 NCBI chr32:37,653,163...37,679,577
Ensembl chr32:37,653,035...37,678,398 		JBrowse link
G METTL16 methyltransferase 16, RNA N6-adenosine enables IEA Ensembl GO_REF:0000107 NCBI chr 9:46,491,503...46,566,752
Ensembl chr 9:46,496,963...46,558,313 		JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit enables IEA
IBA		 Ensembl
UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr15:18,528,755...18,546,303
Ensembl chr15:18,528,772...18,546,531 		JBrowse link
G TMT1A thiol methyltransferase 1A enables IEA Ensembl GO_REF:0000107 NCBI chr27:3,858,792...3,866,350
Ensembl chr27:3,857,454...3,866,448 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      catalytic activity, acting on a nucleic acid 614
        catalytic activity, acting on RNA 381
          RNA methyltransferase activity 65
            mRNA methyltransferase activity 15
              internal mRNA (guanine-N7-)-methyltransferase activity 1
              mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 1
              mRNA (adenine-N1-)-methyltransferase activity 2
              mRNA (cytidine-5-)-methyltransferase activity 2
              mRNA (nucleoside-2'-O-)-methyltransferase activity 3
              mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1
              mRNA m(6)A methyltransferase activity 4
Path 2
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      transferase activity 2314
        transferase activity, transferring one-carbon groups 216
          methyltransferase activity 201
            RNA methyltransferase activity 65
              mRNA methyltransferase activity 15
                internal mRNA (guanine-N7-)-methyltransferase activity 1
                mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 1
                mRNA (adenine-N1-)-methyltransferase activity 2
                mRNA (cytidine-5-)-methyltransferase activity 2
                mRNA (nucleoside-2'-O-)-methyltransferase activity 3
                mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1
                mRNA m(6)A methyltransferase activity 4
paths to the root