RNF8 (ring finger protein 8) - Rat Genome Database

Name: RNF8
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: RNF8 (ring finger protein 8) Canis lupus familiaris

Analyze

Symbol:

RNF8 (Ensembl: CMTR1)

Name:

ring finger protein 8 (Ensembl:cap methyltransferase 1)

RGD ID:

12336012

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair-dependent chromatin remodeling (ortholog); double-strand break repair via nonhomologous end joining (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); site of double-strand break (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase RNF8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF8 (ring finger protein 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Rnf8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Rnf8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf8 (ring finger protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CMTR1 (cap methyltransferase 1)	HGNC	Ensembl
Homo sapiens (human):	TBC1D22B (TBC1 domain family member 22B)	HGNC	EggNOG

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	6,380,365 - 6,415,407 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	6,292,459 - 6,415,382 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	6,398,291 - 6,433,355 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	6,844,755 - 6,879,956 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	6,844,708 - 6,970,087 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	6,381,196 - 6,416,424 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	6,463,623 - 6,498,627 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	6,562,602 - 6,597,564 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

7-methylguanosine mRNA capping (IEA)

cell division (IEA)

chromatin organization (IEA)

DNA damage response (ISO)

DNA repair (IEA)

DNA repair-dependent chromatin remodeling (ISO)

double-strand break repair (IEA)

double-strand break repair via nonhomologous end joining (ISO)

epigenetic regulation of gene expression (ISO)

isotype switching (ISO)

methylation (IEA)

mRNA modification (IEA)

negative regulation of transcription elongation by RNA polymerase II (ISO)

positive regulation of DNA repair (IEA)

positive regulation of double-strand break repair via homologous recombination (ISO)

protein autoubiquitination (ISO)

protein K48-linked ubiquitination (ISO)

protein K6-linked ubiquitination (ISO)

protein K63-linked ubiquitination (IEA)

protein ubiquitination (IEA)

response to ionizing radiation (IEA)

signal transduction in response to DNA damage (ISO)

sperm DNA condensation (ISO)

ubiquitin-dependent protein catabolic process (ISO)

Cellular Component

chromosome (IEA)

chromosome, telomeric region (IEA)

cytoplasm (IEA)

cytosol (ISO)

midbody (IEA)

nucleoplasm (ISO)

nucleus (IEA)

site of double-strand break (ISO)

ubiquitin ligase complex (IEA)

Molecular Function

chromatin binding (IEA)

GTPase activator activity (IEA)

histone binding (IEA)

identical protein binding (ISO)

metal ion binding (IEA)

methyltransferase activity (IEA)

mRNA (nucleoside-2'-O-)-methyltransferase activity (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

transferase activity (IEA)

ubiquitin binding (IEA)

ubiquitin protein ligase activity (ISO)

ubiquitin protein ligase binding (ISO)

ubiquitin-protein transferase activity (IEA)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RNF8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	6,380,365 - 6,415,407 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	6,292,459 - 6,415,382 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	6,398,291 - 6,433,355 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	6,844,755 - 6,879,956 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	6,844,708 - 6,970,087 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	6,381,196 - 6,416,424 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	6,463,623 - 6,498,627 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	6,562,602 - 6,597,564 (+)	NCBI		UU_Cfam_GSD_1.0

RNF8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	37,353,983 - 37,394,734 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	37,353,979 - 37,394,734 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	37,321,759 - 37,362,510 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	37,429,726 - 37,470,492 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	37,429,768 - 37,470,491	NCBI
Celera	6	38,876,721 - 38,917,497 (+)	NCBI		Celera
Cytogenetic Map	6	p21.2	NCBI
HuRef	6	37,040,684 - 37,081,344 (+)	NCBI		HuRef
CHM1_1	6	37,323,524 - 37,364,290 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	37,177,541 - 37,218,292 (+)	NCBI		T2T-CHM13v2.0

Rnf8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	29,833,763 - 29,860,638 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	29,833,764 - 29,863,965 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	29,614,789 - 29,641,664 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	29,614,790 - 29,644,991 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	29,751,776 - 29,778,604 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	28,828,664 - 28,855,463 (+)	NCBI		MGSCv36	mm8
MGSCv36	17	29,341,843 - 29,368,671 (+)	NCBI		MGSCv36	mm8
Celera	17	30,155,441 - 30,176,366 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	15.45	NCBI

Rnf8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	7,683,890 - 7,708,437 (+)	NCBI		GRCr8
mRatBN7.2	20	7,682,258 - 7,710,448 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	7,682,322 - 7,708,491 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	8,385,289 - 8,409,776 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	7,746,451 - 7,770,938 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	8,219,662 - 8,243,816 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	8,285,380 - 8,309,858 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	8,285,296 - 8,309,908 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	10,484,857 - 10,509,126 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	7,929,802 - 7,954,697 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	7,930,028 - 7,954,924 (+)	NCBI
Celera	20	9,219,236 - 9,244,017 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Rnf8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	5,809,082 - 5,832,057 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	5,807,592 - 5,832,213 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	51,825,574 - 51,862,276 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	47,695,597 - 47,732,307 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	36,918,705 - 36,955,380 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	38,108,414 - 38,145,949 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	38,108,414 - 38,145,949 (+)	Ensembl	panpan1.1		panPan2

Rnf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	41,838,907 - 41,886,084 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936476	22,074,146 - 22,121,286 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	32,931,786 - 32,970,585 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	32,931,786 - 32,969,536 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	37,836,029 - 37,874,578 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	34,754,186 - 34,787,676 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	34,751,945 - 34,787,632 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	37,301,000 - 37,337,835 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	20,679,867 - 20,714,522 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	20,683,133 - 20,714,469 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RNF8
256 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038491687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038617776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_859637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000002276 ⟹ ENSCAFP00000002112

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	6,292,459 - 6,365,793 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000002283 ⟹ ENSCAFP00000002119

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	6,380,394 - 6,415,382 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000047572 ⟹ ENSCAFP00000041311

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	6,381,867 - 6,415,382 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000074096 ⟹ ENSCAFP00000064677

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	6,292,459 - 6,365,440 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000085175 ⟹ ENSCAFP00000053376

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	6,292,459 - 6,415,382 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019377 ⟹ ENSCAFP00845015149

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,844,708 - 6,970,067 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019547 ⟹ ENSCAFP00845015287

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,844,708 - 6,879,950 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019592 ⟹ ENSCAFP00845015325

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,844,708 - 6,879,573 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019631 ⟹ ENSCAFP00845015355

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,845,326 - 6,879,950 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019694 ⟹ ENSCAFP00845015409

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,919,403 - 6,970,083 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019770 ⟹ ENSCAFP00845015473

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,919,416 - 6,970,087 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845019872 ⟹ ENSCAFP00845015564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	6,919,436 - 6,970,084 (+)	Ensembl

RefSeq Acc Id:

XM_038491687 ⟹ XP_038347615

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	6,381,196 - 6,416,424 (+)	NCBI

RefSeq Acc Id:

XM_038553916 ⟹ XP_038409844

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	6,562,602 - 6,597,564 (+)	NCBI

RefSeq Acc Id:

XM_038617776 ⟹ XP_038473704

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	6,463,623 - 6,498,627 (+)	NCBI

RefSeq Acc Id:

XM_038683373 ⟹ XP_038539301

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	6,844,755 - 6,879,956 (+)	NCBI

RefSeq Acc Id:

XM_859637 ⟹ XP_864730

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	6,380,365 - 6,415,407 (+)	NCBI
Dog10K_Boxer_Tasha	12	6,398,291 - 6,433,355 (+)	NCBI

Sequence:

show sequence

TTCACATCGATCGCGAGCGCGTAGCGATTGCTTCTGTCTGTTGTTTAGTTATGGCGCCGGCGAC
GAGGCTGAGAGGCGGCGGGAACCCGGGCGGGGGTCTCGCTCTGTGCTGACCGCGACCTGGGGCA
CACGGGGCTATGGAGGAGCCCGGCTCGTTGGTCACGGGAGACCGCGCCGGTGGCCGGAGGTGGT
GCTTGCGGCGGGCCAGGATGAACGCCGAGTGGCTGCTGCTGGAGGACGGAAACGAGGTGACTAT
AGGGCGAGGATTTGGTGTCACATACCAACTGGTATCAAAAATCTGCCCTCTGATGATTTCCCGA
AACCACTGTGTTTTGAAGCAGAACGTCGAGGGCCAGTGGACAATTATGGATAACAAGAGTCTGA
ATGGTGTTTGGCTGAACAGAGAACGTCTAGAACCTTTAAAGGTCTATTCTATCCATAAAGGAGA
CCACATCCAGCTCGGGGTACCTCTAGAGAATAAGGAGAATGCGGAGTATGAGTATGAAGTTACT
GAAGAAGACTGGGAGAGGATGTATCCTTGTCTTGCTCCAAAGAATGATCAGATTATAGGAAAAA
ATAGGGGTTTGAGAACTAAAAGGAAATTCAGTTTGGATGAATTGGAGGGTCCTGGAGCTGAAGG
CCCCTCACATTTGAAATCCAAAATAAGTAAAGTGTCTTACAAACCTGGTCAGCCGGTGAAATCT
CATGGAAAAGGTGAGGTGGCCAGTCAGCCTTCTGAATATTTGGATCCTAAGTTGACATCTCTTG
AGCTAAGTGAGAAGGCCACAGATGCTCATGTTTACCCTTCCTCCACAAAAGTCGTAGCGCTTCA
TCATAAGAAGCAGAAAGCCTCAAGTCCTTCAGCATCTCAGAGCAGCTTAGAGCTGTTCAAGGTG
ACTATGTCCAGGATTCTGAAGCTGAAAACACAAATGCAGGAAAAACAGGTAGCTGTCCTGAATG
TGAAAAGGCAGACCCAAAAAGGGAACTCAAAGAAAATTGTGAAAATGGAGAAGGAACTGCAGGA
CTTACAGTCCCAGCTGTGTGCAGAGCAGGCCCAGCAGCAGGCCAGAGTGGAACAGCTAGAGAAG
ACTTTCCAAGAAGAGGAGCAGCATCTCCAGGGTTTGGAGAAGGATCAAGGAGAAGAGGACCTGA
AGCAACAGCTGGCCCAGGCGCTGCAGGAGCATCGGGCTCTAATGGAAGAGCTAAATCGCAGCAA
GAAGGACTTTGAAGCAATCATTCAAGCCAAGAACAAAGAATTGGAACAGACCAAGGAAGAGAAG
GAGAAGATGCAAGCCCAGAAGGAGGAAGTCCTTAGCCACGTGAATGATGTGCTAGAGAATGAGC
TCCAGTGTATTATTTGCTCAGAATACTTCATTGAGGCTGTCACCTTGAACTGTGCCCACAGTTT
CTGCTCCTACTGTATCAATGAATGGATGAAGCGGAAGGTAGAATGCCCCATTTGTCGGAAGGAC
ATCAAGTCCAAAACCCACTCCCTGGTTCTGGACAATTGCATTAATAAGATGGTAGATAATCTGA
GCTCAGAAGTGAAAGACCGACGAATTGTCCTCATTAGGGAACGAAAAGCAAAGAGACTGTCATG
AAGACCATGCTCCAGGGACATTTGAGGGATTGCCAGGCAACAGGAGCTTGAGATAGTCTGGAGA
ATTCCCTGTGGCCAGGTCTTGGGCCGCTCTGAGATAGAGCATGGGATGGAACCACACGGGACAG
AGACTGAGTTAGGAAGTCCTCATGAGCCTCCATGTTGGCCGGCGGAGCTGCCACCATTGTCTGA
GGTGCCACCGGTCCTCGCCGTGCAGACTGCTTCAGGGTACTTGATAGACTCTGCTTCACTGTGT
GTTGAATGGGTTATGTATTTCTGTTTTGCTTTTTAAGTTTATTGTTTTATCGTTTTGGTACCTC
AGAAGCACCTCTATTGGCATTTGTTTTGGATGGGTTGGGTGTACCGTTGTGGCTGCCCCTAGAA
GTTAAGGCAGCCTCTTTTGGAGAGGATGGCCTACCTCTTTGTGAAAACAAGATGTCATTTCCTG
GAAATAAAATGTAAAGCGTATCAGTTGCTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038347615	(Get FASTA)	NCBI Sequence Viewer
	XP_038409844	(Get FASTA)	NCBI Sequence Viewer
	XP_038473704	(Get FASTA)	NCBI Sequence Viewer
	XP_038539301	(Get FASTA)	NCBI Sequence Viewer
	XP_864730	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000002119.4
	ENSCAFP00000053376.2
	ENSCAFP00000064677.2
	ENSCAFP00030015936.1
	ENSCAFP00040032323.1
	ENSCAFP00040032480.1
	ENSCAFP00040032619.1
	ENSCAFP00845015149.1
	ENSCAFP00845015287
	ENSCAFP00845015287.1
	ENSCAFP00845015325.1
	ENSCAFP00845015355.1
	ENSCAFP00845015564.1

RefSeq Acc Id:

XP_864730 ⟸ XM_859637

- UniProtKB:

A0A8C0QWT5 (UniProtKB/TrEMBL), A0A8C0T933 (UniProtKB/TrEMBL), A0A8P0S7J0 (UniProtKB/TrEMBL), A0A8C0MWH3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEEPGSLVTGDRAGGRRWCLRRARMNAEWLLLEDGNEVTIGRGFGVTYQLVSKICPLMISRNHC
VLKQNVEGQWTIMDNKSLNGVWLNRERLEPLKVYSIHKGDHIQLGVPLENKENAEYEYEVTEED
WERMYPCLAPKNDQIIGKNRGLRTKRKFSLDELEGPGAEGPSHLKSKISKVSYKPGQPVKSHGK
GEVASQPSEYLDPKLTSLELSEKATDAHVYPSSTKVVALHHKKQKASSPSASQSSLELFKVTMS
RILKLKTQMQEKQVAVLNVKRQTQKGNSKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQ
EEEQHLQGLEKDQGEEDLKQQLAQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKM
QAQKEEVLSHVNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKS
KTHSLVLDNCINKMVDNLSSEVKDRRIVLIRERKAKRLS

hide sequence

Ensembl Acc Id:

ENSCAFP00000064677 ⟸ ENSCAFT00000074096

Ensembl Acc Id:

ENSCAFP00000041311 ⟸ ENSCAFT00000047572

Ensembl Acc Id:

ENSCAFP00000002119 ⟸ ENSCAFT00000002283

Ensembl Acc Id:

ENSCAFP00000002112 ⟸ ENSCAFT00000002276

Ensembl Acc Id:

ENSCAFP00000053376 ⟸ ENSCAFT00000085175

RefSeq Acc Id:

XP_038347615 ⟸ XM_038491687

RefSeq Acc Id:

XP_038473704 ⟸ XM_038617776

RefSeq Acc Id:	XP_038539301 ⟸ XM_038683373
- UniProtKB:	A0A8C0QWT5 (UniProtKB/TrEMBL), A0A8C0T933 (UniProtKB/TrEMBL), A0A8P0S7J0 (UniProtKB/TrEMBL), A0A8C0MWH3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038409844 ⟸ XM_038553916
- UniProtKB:	A0A8C0MWH3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845015287 ⟸ ENSCAFT00845019547

Ensembl Acc Id:

ENSCAFP00845015325 ⟸ ENSCAFT00845019592

Ensembl Acc Id:

ENSCAFP00845015149 ⟸ ENSCAFT00845019377

Ensembl Acc Id:

ENSCAFP00845015409 ⟸ ENSCAFT00845019694

Ensembl Acc Id:

ENSCAFP00845015355 ⟸ ENSCAFT00845019631

Ensembl Acc Id:

ENSCAFP00845015473 ⟸ ENSCAFT00845019770

Ensembl Acc Id:

ENSCAFP00845015564 ⟸ ENSCAFT00845019872

Protein Domains

FHA Rab-GAP TBC RING-type

Promoters

RGD ID:

13685408

Promoter ID:

EPDNEW_C3476

Type:

multiple initiation site

Name:

RNF8_1

Description:

ring finger protein 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	6,380,394 - 6,380,454	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000001477	UniProtKB/TrEMBL
	ENSCAFG00000030176	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009853	UniProtKB/TrEMBL
	ENSCAFG00040020080	UniProtKB/TrEMBL
	ENSCAFG00845010951	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000002283.5	UniProtKB/TrEMBL
	ENSCAFT00000074096.2	UniProtKB/TrEMBL
	ENSCAFT00000085175.2	UniProtKB/TrEMBL
	ENSCAFT00030018250.1	UniProtKB/TrEMBL
	ENSCAFT00040037107.1	UniProtKB/TrEMBL
	ENSCAFT00040037275.1	UniProtKB/TrEMBL
	ENSCAFT00040037425.1	UniProtKB/TrEMBL
	ENSCAFT00845019377.1	UniProtKB/TrEMBL
	ENSCAFT00845019547	ENTREZGENE
	ENSCAFT00845019547.1	UniProtKB/TrEMBL
	ENSCAFT00845019592.1	UniProtKB/TrEMBL
	ENSCAFT00845019631.1	UniProtKB/TrEMBL
	ENSCAFT00845019872.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
	2.60.200.20	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	3.40.50.12760	UniProtKB/TrEMBL
	DNA ligase/mRNA capping enzyme	UniProtKB/TrEMBL
	putative rabgap domain of human tbc1 domain family member 14 like domains	UniProtKB/TrEMBL
	Ypt/Rab-GAP domain of gyp1p, domain 1	UniProtKB/TrEMBL
	Ypt/Rab-GAP domain of gyp1p, domain 3	UniProtKB/TrEMBL
InterPro	FHA_dom	UniProtKB/TrEMBL
	G_patch_dom	UniProtKB/TrEMBL
	mRNA_Cap_2O-Ribose_MeTrfase	UniProtKB/TrEMBL
	Rab-GTPase-TBC_dom	UniProtKB/TrEMBL
	Rab-GTPase_TBC_sf	UniProtKB/TrEMBL
	RNA_MeTrfase_FtsJ_dom	UniProtKB/TrEMBL
	RNF8	UniProtKB/TrEMBL
	RrmJ-type_MeTrfase	UniProtKB/TrEMBL
	SAM-dependent_MTases_sf	UniProtKB/TrEMBL
	SMAD_FHA_dom_sf	UniProtKB/TrEMBL
	WW_dom	UniProtKB/TrEMBL
	Znf_C3HC4_RING-type	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	cfa:481775	UniProtKB/TrEMBL
NCBI Gene	RNF8	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE RNF8	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE RNF8	UniProtKB/TrEMBL
	PTHR16121:SF0	UniProtKB/TrEMBL
	TBC1 DOMAIN FAMILY MEMBER 22B	UniProtKB/TrEMBL
	TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	FHA	UniProtKB/TrEMBL
	FtsJ	UniProtKB/TrEMBL
	G-patch	UniProtKB/TrEMBL
	RabGAP-TBC	UniProtKB/TrEMBL
	zf-C3HC4	UniProtKB/TrEMBL
PIRSF	E3_ubiquit_lig_RNF8	UniProtKB/TrEMBL
PROSITE	FHA_DOMAIN	UniProtKB/TrEMBL
	G_PATCH	UniProtKB/TrEMBL
	SAM_MT_RRMJ	UniProtKB/TrEMBL
	TBC_RABGAP	UniProtKB/TrEMBL
	WW_DOMAIN_1	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	FHA	UniProtKB/TrEMBL
	G_patch	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SM00456	UniProtKB/TrEMBL
	TBC	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF47923	UniProtKB/TrEMBL
	SSF49879	UniProtKB/TrEMBL
	SSF53335	UniProtKB/TrEMBL
UniProt	A0A8C0MWH3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QWT5	ENTREZGENE
	A0A8C0T8H6_CANLF	UniProtKB/TrEMBL
	A0A8C0T933	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TBQ1_CANLF	UniProtKB/TrEMBL
	A0A8I3NCR7_CANLF	UniProtKB/TrEMBL
	A0A8I3NGC5_CANLF	UniProtKB/TrEMBL
	A0A8I3NHC7_CANLF	UniProtKB/TrEMBL
	A0A8I3NIN9_CANLF	UniProtKB/TrEMBL
	A0A8I3RYA7_CANLF	UniProtKB/TrEMBL
	A0A8P0S7J0	ENTREZGENE
	A0A8P0T5W4_CANLF	UniProtKB/TrEMBL
UniProt Secondary	A0A8P0S7J0	UniProtKB/TrEMBL
VGNC ID	VGNC:45676	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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