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ONTOLOGY REPORT - ANNOTATIONS

Term:protein processing involved in protein targeting to mitochondrion
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Accession:GO:0006627 term browser browse the term
Definition:The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
Synonyms:broad_synonym: mitochondrial processing
 related_synonym: mitochondrial protein processing during import


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protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IMMP2L inner mitochondrial membrane peptidase subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15814844) InterPro
MGI		 PMID:15814844 GO_REF:0000002 NCBI chr14:50,487,679...51,336,906 JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:49,073,124...49,083,302
Ensembl chr 9:49,073,108...49,224,961 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta involved_in ISO
IEA		 RGD
Ensembl		 PMID:12433926 GO_REF:0000107 RGD:13463464 NCBI chr18:16,894,240...16,906,988
Ensembl chr18:16,894,276...16,906,979 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr26:16,228,831...16,244,104
Ensembl chr26:16,234,710...16,240,012 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17099
    localization 5328
      establishment of localization 4673
        establishment of protein localization 1636
          protein targeting 277
            protein targeting to mitochondrion 95
              protein processing involved in protein targeting to mitochondrion 4
                negative regulation of protein processing involved in protein targeting to mitochondrion 1
                regulation of protein processing involved in protein targeting to mitochondrion + 1
Path 2
Term Annotations click to browse term
  biological_process 17099
    localization 5328
      macromolecule localization 2959
        cellular macromolecule localization 2532
          protein localization 2519
            protein localization to organelle 974
              protein localization to mitochondrion 127
                establishment of protein localization to mitochondrion 117
                  protein targeting to mitochondrion 95
                    protein processing involved in protein targeting to mitochondrion 4
                      negative regulation of protein processing involved in protein targeting to mitochondrion 1
                      regulation of protein processing involved in protein targeting to mitochondrion + 1
paths to the root