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ONTOLOGY REPORT - ANNOTATIONS


Term:epidermal growth factor receptor activity
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Accession:GO:0005006 term browser browse the term
Definition:Combining with an epidermal growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Synonyms:exact_synonym: EGF receptor activity;   EGFR;   TGF-alpha receptor activity;   epidermal growth factor-activated receptor activity;   transforming growth factor-alpha receptor activity
 alt_id: GO:0005023



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epidermal growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efemp1 EGF containing fibulin extracellular matrix protein 1 enables ISO
ISS
IEA
(PMID:19804359)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:19804359 GO_REF:0000024 GO_REF:0000107 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Egfr epidermal growth factor receptor enables
contributes_to
TAS
IDA
IMP
ISO
IBA
(PMID:11336639), (PMID:12435727), (PMID:17115032), (PMID:2176151), (PMID:22732145)
GO_REF:0000033
(PMID:12828935)
MGI:1856402|MGI:95410 (PMID:11823423), (PMID:11940581), (PMID:14712229), (PMID:16357442), (PMID:18701712), (PMID:21946538), (PMID:23457600), (PMID:6248866), (PMID:7752576), (PMID:9529375)
RGD
GO_Central
PMID:2176151 PMID:6248866 PMID:7752576 PMID:9529375 PMID:11336639 More... GO_REF:0000033, RGD:625656, RGD:70386, RGD:1581908 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 enables IEA
ISO
GO_REF:0000107
MGI:96070 (PMID:12621152)
Ensembl
RGD
PMID:12621152 GO_REF:0000107 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Nrg2 neuregulin 2 IDA RGD PMID:9348101 RGD:1304015 NCBI chr18:27,616,542...27,798,505
Ensembl chr18:27,619,661...27,798,505
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      catalytic activity, acting on a protein 2445
        protein kinase activity 622
          transmembrane receptor protein kinase activity 79
            transmembrane receptor protein tyrosine kinase activity 61
              epidermal growth factor receptor activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      transferase activity 2398
        transferase activity, transferring phosphorus-containing groups 972
          kinase activity 804
            protein kinase activity 622
              protein tyrosine kinase activity 136
                transmembrane receptor protein tyrosine kinase activity 61
                  epidermal growth factor receptor activity 4
paths to the root