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ONTOLOGY REPORT - ANNOTATIONS

Term:lysine-tRNA ligase activity
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Accession:GO:0004824 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
Synonyms:exact_synonym: lysyl-tRNA synthetase activity
 related_synonym: L-lysine-transfer RNA ligase activity;   L-lysine:tRNALys ligase (AMP-forming);   lysine translase activity;   lysine-tRNA synthetase activity;   lysyl-transfer RNA synthetase activity;   lysyl-transfer ribonucleate synthetase activity
 xref: EC:6.1.1.6;   MetaCyc:LYSINE--TRNA-LIGASE-RXN;   RHEA:20792;   reactome:R-HSA-380008 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate";   reactome:R-HSA-380233 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate"


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lysine-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kars1 lysyl-tRNA synthetase 1 enables IDA
ISO
IEA
IBA		 (PMID:10952987), (PMID:23159739), (PMID:9278442)
PMID:6315704
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:9278442 PMID:10952987 PMID:23159739 PMID:7372681 PMID:7082655 More... GO_REF:0000002 GO_REF:0000033, RGD:2303393, RGD:2303394, RGD:12911009 NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      ligase activity 181
        ligase activity, forming carbon-oxygen bonds 45
          aminoacyl-tRNA ligase activity 45
            lysine-tRNA ligase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      catalytic activity, acting on a nucleic acid 632
        catalytic activity, acting on RNA 391
          catalytic activity, acting on a tRNA 136
            aminoacyl-tRNA ligase activity 45
              lysine-tRNA ligase activity 1
paths to the root