Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
go back to main search page
Accession:GO:0004572 term browser browse the term
Definition:Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
Synonyms:exact_synonym: mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity
 narrow_synonym: ManII activity;   mannosidase II activity
 related_synonym: 1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity;   GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity;   Golgi alpha-mannosidase II;   alpha-(1,3/6)-mannosidase activity;   alpha-D-mannosidase II;   alpha-mannosidase II;   exo-1,3-1,6-alpha-mannosidase activity
 xref: EC:3.2.1.114;   MetaCyc:3.2.1.114-RXN;   RHEA:56052;   reactome:R-HSA-975814 "Trimming of mannoses on the alpha1,6 arm by MAN2A1"

Please select species to view GViewer data.

show annotations for term's descendants           Sort by:
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G N Man2a1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chrNW_004624743:27,607,094...27,791,612 JBrowse link
G G MAN2A1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chr23:13,094,383...13,268,286
Ensembl chr23:13,094,538...13,268,283 		JBrowse link
G P MAN2A1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chr 2:114,675,786...114,853,133
Ensembl chr 2:114,675,917...114,855,548 		JBrowse link
G S Man2a1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chrNW_004936531:4,331,354...4,494,110
Ensembl chrNW_004936531:4,331,200...4,494,131 		JBrowse link
G D MAN2A1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chr 3:2,340,392...2,477,458
Ensembl chr 3:2,330,959...2,488,393 		JBrowse link
G B MAN2A1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chr 5:105,034,104...105,219,011
Ensembl chr 5:110,841,349...111,025,187 		JBrowse link
G C Man2a1 mannosidase alpha class 2A member 1 enables ISO PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chrNW_004955418:5,027,962...5,191,346
Ensembl chrNW_004955418:5,027,174...5,191,346 		JBrowse link
G R Man2a1 mannosidase, alpha, class 2A, member 1 enables IDA PMID:1885615 UniProt PMID:1885615 RGD:38501079 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349 		JBrowse link
G M Man2a1 mannosidase 2, alpha 1 enables ISO
IEA		 MGI
RHEA
UniProt		 GO_REF:0000003 GO_REF:0000096 GO_REF:0000116 MGI:4417868 NCBI chr17:64,907,683...65,062,105
Ensembl chr17:64,907,731...65,062,105 		JBrowse link
G H MAN2A1 mannosidase alpha class 2A member 1 enables TAS
IEA		 (PMID:8524845) PINC
Ensembl
UniProt
RHEA		 PMID:8524845 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 5:109,689,927...109,869,625
Ensembl chr 5:109,689,927...109,869,625 		JBrowse link
G M Man2a2 mannosidase 2, alpha 2 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 MGI:2152096 NCBI chr 7:79,998,843...80,021,222
Ensembl chr 7:79,998,845...80,021,123 		JBrowse link
G H MAN2A2 mannosidase alpha class 2A member 2 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr15:90,902,382...90,922,585
Ensembl chr15:90,902,218...90,922,584 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 189980
    catalytic activity 54016
      hydrolase activity 22775
        hydrolase activity, acting on glycosyl bonds 1221
          hydrolase activity, hydrolyzing O-glycosyl compounds 922
            mannosidase activity 152
              alpha-mannosidase activity 141
                mannosyl-oligosaccharide mannosidase activity 84
                  mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 12
paths to the root