Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:nitric-oxide synthase activity
go back to main search page
Accession:GO:0004517 term browser browse the term
Definition:Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
Synonyms:related_synonym: L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity;   NADPH-diaphorase activity;   NO synthase activity;   endothelium-derived relaxation factor-forming enzyme activity;   endothelium-derived relaxing factor synthase activity;   nitric oxide synthetase activity
 xref: EC:1.14.13.39;   MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN;   RHEA:19897;   reactome:R-HSA-202127 "eNOS synthesizes NO";   reactome:R-HSA-418436 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO)"



show annotations for term's descendants           Sort by:
nitric-oxide synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 enables TAS
IDA
IEA
ISO
IBA
GO_REF:0000116
GO_REF:0000003
PMID:1383204
PMID:17029414
PMID:18591664
PMID:23549614
GO_REF:0000117
(PMID:1689048), (PMID:35772285)
PMID:1712077
GO_REF:0000033
(PMID:11591728), (PMID:7545544)
RHEA
UniProt
RGD
GO_Central
PMID:1689048 PMID:7545544 PMID:11591728 PMID:35772285 PMID:12526033 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:727494, RGD:1598372, RGD:1580263, RGD:1358520, RGD:8553334, RGD:1598372, RGD:8554165, RGD:14995314, RGD:329955539, RGD:401827139 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 enables TAS
IDA
IEA
ISO
IBA
GO_REF:0000003
GO_REF:0000116
PMID:9851365
GO_REF:0000117
(PMID:35772285), (PMID:7504305), (PMID:7682706)
GO_REF:0000033
(PMID:1383204), (PMID:9271491)
UniProt
RHEA
RGD
GO_Central
PMID:1383204 PMID:7504305 PMID:7682706 PMID:9271491 PMID:35772285 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:625548, RGD:70247, RGD:1580262, RGD:8656011 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 enables IMP
IDA
IEA
ISO
IBA
GO_REF:0000003
GO_REF:0000116
GO_REF:0000117
(PMID:1378832), (PMID:19666465), (PMID:23707606), (PMID:35772285), (PMID:7488039)
GO_REF:0000033
MGI:1857229 (PMID:15647265)
UniProt
RHEA
RGD
GO_Central
PMID:1378832 PMID:7488039 PMID:15647265 PMID:19666465 PMID:23707606 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:628542, RGD:628542 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link

Term paths to the root