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ONTOLOGY REPORT - ANNOTATIONS

Term:fatty acid synthase activity
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Accession:GO:0004312 term browser browse the term
Definition:Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
Synonyms:related_synonym: acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
 xref: EC:2.3.1.85;   MetaCyc:FATTY-ACID-SYNTHASE-RXN;   RHEA:14993;   Reactome:R-HSA-163756 "Formation of fatty acid synthase (FAS) dimer";   Reactome:R-HSA-75872 "Conversion of malonyl-CoA and acetyl-CoA to palmitate"


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fatty acid synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FASN fatty acid synthase enables ISO
IEA
EXP
IBA		 (PMID:18455495) RGD
Ensembl
UniProt
Reactome
GO_Central		 PMID:15715522 PMID:18062843 PMID:18455495 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 RGD:2317315 RGD:2317317 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
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Term Annotations click to browse term
  molecular_function 19683
    catalytic activity 6023
      transferase activity 2450
        acyltransferase activity 759
          acyltransferase activity, transferring groups other than amino-acyl groups 239
            fatty acid synthase activity 1
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