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ONTOLOGY REPORT - ANNOTATIONS

Term:ATP citrate synthase activity
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Accession:GO:0003878 term browser browse the term
Definition:Catalysis of the reaction: acetyl-CoA + ADP + H+ + oxaloacetate + phosphate = ATP + citrate + CoA.
Comment:Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
Synonyms:related_synonym: ATP citrate (pro-S)-lyase activity;   ATP-citric lyase activity;   ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity;   ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating);   acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating];   acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity;   acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating);   adenosine triphosphate citrate lyase activity;   citrate cleavage enzyme activity;   citrate-ATP lyase activity;   citric cleavage enzyme activity
 alt_id: GO:0046913
 xref: EC:2.3.3.8;   KEGG_REACTION:R00352;   MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN;   RHEA:21160;   reactome:R-HSA-75848 "ACLY tetramer transforms CIT to Ac-CoA"


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ATP citrate synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACLY ATP citrate lyase enables ISO
IEA
IDA
TAS
IBA		 (PMID:10653665), (PMID:1371749), (PMID:19286649), (PMID:9116495)
(PMID:23932781)		 RGD
UniProt
InterPro
RHEA
GO_Central		 PMID:1371749 PMID:2295639 PMID:9116495 PMID:10653665 PMID:11735100 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 RGD:2317315 RGD:2317316 RGD:631761 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
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Path 1
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  molecular_function 19683
    catalytic activity 6024
      transferase activity 2450
        acyltransferase activity 759
          acyltransferase activity, acyl groups converted into alkyl on transfer 5
            ATP citrate synthase activity 1
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