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ONTOLOGY REPORT - ANNOTATIONS
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Term:
regulation of heart rate by chemical signal
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Accession:
GO:0003062
browse the term
Definition:
The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
Synonyms:
exact_synonym:
chemical cardiac chronotropy; chemical signal regulation of heart rate
related_synonym:
chemical signal regulation of heart contraction rate
show annotations for term's descendants Sort by:
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object name
position
reference
evidence
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Rat (5)
Mouse (5)
Human (9)
Chinchilla (4)
Bonobo (6)
Dog (6)
Squirrel (5)
Pig (5)
Green Monkey (4)
Naked Mole-rat (4)
All
Genes (5)
regulation of heart rate by chemical signal
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ffar3
free fatty acid receptor 3
acts_upstream_of_or_within
ISO
MGI:5013799 (PMID:21518883)
RGD
PMID:21518883
NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
G
Nos1ap
nitric oxide synthase 1 adaptor protein
involved_in
ISO
(PMID:19247217)
RGD
PMID:19247217
NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949
G
Srebf1
sterol regulatory element binding transcription factor 1
acts_upstream_of_or_within
ISO
MGI:2177773 (PMID:18060044)
RGD
PMID:18060044
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
negative regulation of heart rate by acetylcholine
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Chrm3
cholinergic receptor, muscarinic 3
IMP
RGD
PMID:9316844
RGD:2303391
NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
positive regulation of heart rate by epinephrine
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Tpm1
tropomyosin 1
involved_in
ISO
(PMID:17556658)
RGD
PMID:17556658
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20069
biological regulation
13554
regulation of biological quality
3417
regulation of heart rate
116
regulation of heart rate by chemical signal
5
negative regulation of heart rate by acetylcholine
+
1
positive regulation of heart rate by epinephrine
+
1
positive regulation of heart rate by norepinephrine
+
0
regulation of heart rate by hormone
0
Path 2
Term
Annotations
biological_process
20069
multicellular organismal process
8906
system process
3539
circulatory system process
620
blood circulation
591
heart contraction
257
regulation of heart contraction
211
regulation of heart rate
116
regulation of heart rate by chemical signal
5
negative regulation of heart rate by acetylcholine
+
1
positive regulation of heart rate by epinephrine
+
1
positive regulation of heart rate by norepinephrine
+
0
regulation of heart rate by hormone
0