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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of natural killer cell mediated immunity
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Accession:GO:0002717 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
Synonyms:exact_synonym: positive regulation of NK cell mediated immunity;   up regulation of natural killer cell mediated immunity;   upregulation of natural killer cell mediated immunity
 narrow_synonym: activation of natural killer cell mediated immunity;   stimulation of natural killer cell mediated immunity
 related_synonym: positive regulation of NK cell activity;   positive regulation of natural killer cell activity
 alt_id: GO:0045846

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positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidyl peptidase 4 ISO RGD PMID:19327106 RGD:41408336 NCBI chrNW_004624732:3,460,529...3,535,252
Ensembl chrNW_004624732:3,460,118...3,535,249 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24658051) InterPro
MGI
TreeGrafter
Ensembl		 PMID:24658051 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Clnk cytokine dependent hematopoietic cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624755:20,667,325...20,817,497 JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:13,997,903...14,081,140
Ensembl chrNW_004624746:13,997,681...14,081,197 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chrNW_004624793:661,322...675,603
Ensembl chrNW_004624793:661,342...675,675 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:13,997,903...14,081,140
Ensembl chrNW_004624746:13,997,681...14,081,197 		JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)		 UniProt PMID:15811952 MGI:3689781 NCBI chrNW_004624784:10,595,876...10,933,024
Ensembl chrNW_004624784:10,591,824...10,932,981 		JBrowse link
G Cd226 CD226 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (MGI:3689781|PMID:15811952)
(PMID:15811952)		 UniProt
HGNC-UCL		 PMID:15811952 MGI:3689781 NCBI chrNW_004624880:2,229,201...2,240,068 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) UniProt PMID:2204066 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO (PMID:15843532) MGI PMID:15843532 NCBI chrNW_004624749:6,930,025...6,957,241 JBrowse link
G Il21 interleukin 21 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14764669) TreeGrafter
MGI		 PMID:14764669 GO_REF:0000118 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304 		JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within ISO (PMID:8602528) MGI PMID:8602528 NCBI chrNW_004624860:3,454,587...3,461,649
Ensembl chrNW_004624860:3,456,347...3,461,592 		JBrowse link
G Lamp1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chrNW_004624793:661,322...675,603
Ensembl chrNW_004624793:661,342...675,675 		JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:16304049) BHF-UCL PMID:16304049 NCBI chrNW_004624754:24,607,623...24,612,716 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) BHF-UCL PMID:16304049 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) UniProt PMID:19933860 NCBI chrNW_004624804:5,691,011...5,763,314
Ensembl chrNW_004624804:5,690,400...5,763,288 		JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within ISO (PMID:19648922)
(PMID:16127454)		 MGI PMID:16127454 PMID:19648922 NCBI chrNW_004624797:3,120,123...3,142,564
Ensembl chrNW_004624797:3,120,123...3,142,564 		JBrowse link
G Sh2d1b SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:19648922)
(PMID:20962259)		 MGI PMID:19648922 PMID:20962259 NCBI chrNW_004624787:9,077,658...9,078,053 JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) UniProt PMID:16920955 NCBI chrNW_004624794:754,530...796,732 JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:20962259) MGI PMID:20962259 NCBI chrNW_004624828:3,838,464...3,896,698
Ensembl chrNW_004624828:3,838,706...3,897,080 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)		 HGNC-UCL
UniProt		 PMID:15811952 MGI:3689781 NCBI chrNW_004624880:2,229,201...2,240,068 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7903063) UniProt PMID:7903063 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940 		JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589 		JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:10,595,876...10,933,024
Ensembl chrNW_004624784:10,591,824...10,932,981 		JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      immune response 1306
        innate immune response 664
          natural killer cell mediated immunity 53
            positive regulation of natural killer cell mediated immunity 20
              positive regulation of natural killer cell cytokine production 3
              positive regulation of natural killer cell mediated cytotoxicity + 18
              positive regulation of natural killer cell mediated immune response to tumor cell + 6
Path 2
Term Annotations click to browse term
  biological_process 15093
    response to stimulus 8161
      response to external stimulus 2128
        response to external biotic stimulus 1317
          response to other organism 1314
            defense response to other organism 906
              defense response to symbiont 802
                innate immune response 664
                  natural killer cell mediated immunity 53
                    regulation of natural killer cell mediated immunity 32
                      positive regulation of natural killer cell mediated immunity 20
                        positive regulation of natural killer cell cytokine production 3
                        positive regulation of natural killer cell mediated cytotoxicity + 18
                        positive regulation of natural killer cell mediated immune response to tumor cell + 6
paths to the root