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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of natural killer cell mediated immunity
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Accession:GO:0002717 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
Synonyms:exact_synonym: positive regulation of NK cell mediated immunity;   up regulation of natural killer cell mediated immunity;   upregulation of natural killer cell mediated immunity
 narrow_synonym: activation of natural killer cell mediated immunity;   stimulation of natural killer cell mediated immunity
 related_synonym: positive regulation of NK cell activity;   positive regulation of natural killer cell activity
 alt_id: GO:0045846

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positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPP4 dipeptidyl peptidase 4 ISO RGD PMID:19327106 RGD:41408336 NCBI chr10:47,396,605...47,481,478
Ensembl chr10:47,394,093...47,480,893 		JBrowse link
G LOC103221837 popy class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,940,842...42,692,045
Ensembl chr17:41,941,869...41,946,176 		JBrowse link
G LOC119618283 patr class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:13,009,168...13,029,766
Ensembl chr20:13,012,460...13,020,466 		JBrowse link
G CD226 CD226 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24658051) InterPro
MGI
TreeGrafter
Ensembl		 PMID:24658051 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr18:9,790,483...9,900,376
Ensembl chr18:9,811,168...9,901,830 		JBrowse link
G CLNK cytokine dependent hematopoietic cell linker involved_in ISO (MGI:3774350|PMID:16439675) UniProt PMID:16439675 MGI:3774350 NCBI chr27:39,333,435...39,574,050
Ensembl chr27:39,481,226...39,573,795 		JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025 		JBrowse link
G LOC103221837 popy class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,940,842...42,692,045
Ensembl chr17:41,941,869...41,946,176 		JBrowse link
G LOC103221863 mamu class I histocompatibility antigen, alpha chain F involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,899,211...42,903,274 JBrowse link
G LOC103235280 killer cell immunoglobulin-like receptor 3DL2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,422,883...47,442,403
Ensembl chr 6:47,423,896...47,441,895 		JBrowse link
G LOC103240146 UL-16 binding protein 5 involved_in ISO (PMID:18544572) UniProt PMID:18544572 NCBI chr13:21,701,503...21,708,851 JBrowse link
G LOC119618283 patr class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:54,850,831...54,944,915
Ensembl chr 5:54,850,694...54,944,900 		JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:19109136) UniProt PMID:19109136 NCBI chr20:13,009,168...13,029,766
Ensembl chr20:13,012,460...13,020,466 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) UniProt PMID:21825173 NCBI chr11:10,266,581...10,277,175 JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chr 3:91,295,758...91,319,881
Ensembl chr 3:91,295,681...91,321,333 		JBrowse link
G LOC103221863 mamu class I histocompatibility antigen, alpha chain F involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,899,211...42,903,274 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:54,850,831...54,944,915
Ensembl chr 5:54,850,694...54,944,900 		JBrowse link
G CADM1 cell adhesion molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637 		JBrowse link
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:13,009,168...13,029,766
Ensembl chr20:13,012,460...13,020,466 		JBrowse link
G CD226 CD226 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:9,790,483...9,900,376
Ensembl chr18:9,811,168...9,901,830 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)		 HGNC-UCL
UniProt		 PMID:15811952 MGI:3689781 NCBI chr 1:114,233,767...114,265,780
Ensembl chr 1:114,234,357...114,265,994 		JBrowse link
G IL12A interleukin 12A involved_in ISO (PMID:2204066) UniProt PMID:2204066 NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO (PMID:15843532) MGI PMID:15843532 NCBI chr14:6,081,539...6,114,412
Ensembl chr14:6,085,262...6,114,028 		JBrowse link
G IL21 interleukin 21 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14764669) Ensembl
MGI
TreeGrafter		 PMID:14764669 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:10,286,280...10,294,853
Ensembl chr11:10,286,787...10,293,585 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:10,266,581...10,277,175 JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in ISO (PMID:9754572) UniProt PMID:9754572 NCBI chr11:10,181,681...10,192,544 JBrowse link
G KLRF2 killer cell lectin like receptor F2 acts_upstream_of_or_within ISO (PMID:10229823), (PMID:10229828) MGI PMID:10229823 PMID:10229828 NCBI chr11:9,765,192...9,781,662
Ensembl chr11:9,766,837...9,781,420 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:10,207,066...10,223,922
Ensembl chr11:10,207,211...10,223,899 		JBrowse link
G LAG3 lymphocyte activating 3 acts_upstream_of_or_within ISO (PMID:8602528) MGI PMID:8602528 NCBI chr11:6,809,381...6,815,390
Ensembl chr11:6,809,584...6,815,325 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in ISO (PMID:23632890) UniProt PMID:23632890 NCBI chr 3:91,295,758...91,319,881
Ensembl chr 3:91,295,681...91,321,333 		JBrowse link
G LOC103221837 popy class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,940,842...42,692,045
Ensembl chr17:41,941,869...41,946,176 		JBrowse link
G LOC103234825 PVR cell adhesion molecule involved_in ISO (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr 6:38,127,864...38,141,612 JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO (PMID:9841920) MGI PMID:9841920 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOC119618283 patr class I histocompatibility antigen, alpha chain E involved_in IEA Ensembl GO_REF:0000107
G NCR3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:16304049) BHF-UCL PMID:16304049
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,320,791...38,361,419
Ensembl chr 6:38,320,933...38,361,742 		JBrowse link
G RAET1E retinoic acid early transcript 1E involved_in ISO (PMID:18544572) UniProt PMID:18544572 NCBI chr13:21,728,551...21,755,588 JBrowse link
G RAET1E retinoic acid early transcript 1E involved_in IEA Ensembl GO_REF:0000107 Ensembl chr13:21,738,263...21,740,910 JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in ISO (PMID:19933860) UniProt PMID:19933860 NCBI chr26:44,405,007...44,483,291 JBrowse link
G SH2D1A SH2 domain containing 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19648922)
(PMID:16127454)		 Ensembl
MGI		 PMID:16127454 PMID:19648922 GO_REF:0000107
G SH2D1B SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:20962259)
(PMID:19648922)		 MGI PMID:19648922 PMID:20962259 NCBI chr20:1,667,247...1,684,951
Ensembl chr20:1,668,588...1,682,949 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,426,868...3,465,553
Ensembl chr20:3,453,370...3,463,901 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:9841920) MGI PMID:9841920 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:20962259) MGI PMID:20962259 NCBI chr 6:6,337,255...6,415,851 JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:6,337,599...6,404,449 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:9,790,483...9,900,376
Ensembl chr18:9,811,168...9,901,830 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:114,233,767...114,265,780
Ensembl chr 1:114,234,357...114,265,994 		JBrowse link
G IL12A interleukin 12A involved_in ISO (PMID:7903063) UniProt PMID:7903063 NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550 		JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:61,714,293...61,731,835 JBrowse link
G LOC103234825 PVR cell adhesion molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,127,864...38,141,612 JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:38,320,791...38,361,419
Ensembl chr 6:38,320,933...38,361,742 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:13,009,168...13,029,766
Ensembl chr20:13,012,460...13,020,466 		JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM1 cell adhesion molecule 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637 		JBrowse link
G LOC103234825 PVR cell adhesion molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,127,864...38,141,612 JBrowse link
G LOC103240141 UL16-binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) MGI PMID:12645935 NCBI chr13:21,625,381...21,638,933
Ensembl chr13:21,629,092...21,636,623 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:38,320,791...38,361,419
Ensembl chr 6:38,320,933...38,361,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    immune system process 2492
      immune response 1640
        innate immune response 827
          natural killer cell mediated immunity 77
            positive regulation of natural killer cell mediated immunity 37
              positive regulation of natural killer cell cytokine production 9
              positive regulation of natural killer cell mediated cytotoxicity + 33
              positive regulation of natural killer cell mediated immune response to tumor cell + 7
Path 2
Term Annotations click to browse term
  biological_process 16925
    response to stimulus 8685
      response to external stimulus 2465
        response to external biotic stimulus 1584
          response to other organism 1581
            defense response to other organism 1126
              defense response to symbiont 1010
                innate immune response 827
                  natural killer cell mediated immunity 77
                    regulation of natural killer cell mediated immunity 53
                      positive regulation of natural killer cell mediated immunity 37
                        positive regulation of natural killer cell cytokine production 9
                        positive regulation of natural killer cell mediated cytotoxicity + 33
                        positive regulation of natural killer cell mediated immune response to tumor cell + 7
paths to the root