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ONTOLOGY REPORT - ANNOTATIONS

Term:transitional two stage B cell differentiation
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Accession:GO:0002334 term browser browse the term
Definition:The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: T2 stage B cell differentiation;   transitional two stage B lymphocyte differentiation
 related_synonym: transitional two stage B cell development


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transitional two stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (PMID:20543113) RGD PMID:20543113 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3008
      leukocyte activation 1056
        lymphocyte activation 856
          lymphocyte differentiation 444
            B cell differentiation 154
              immature B cell differentiation 24
                transitional stage B cell differentiation 3
                  transitional two stage B cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20069
    developmental process 7067
      cellular developmental process 4781
        cell differentiation 4780
          cell development 3325
            hemopoiesis 1075
              leukocyte differentiation 681
                mononuclear cell differentiation 546
                  lymphocyte differentiation 444
                    B cell differentiation 154
                      immature B cell differentiation 24
                        transitional stage B cell differentiation 3
                          transitional two stage B cell differentiation 1
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