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ONTOLOGY REPORT - ANNOTATIONS

Term:purine-specific mismatch base pair DNA N-glycosylase activity
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Accession:GO:0000701 term browser browse the term
Definition:Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
Synonyms:narrow_synonym: A/G-specific adenine DNA glycosylase activity
 xref: EC:3.2.2.31


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purine-specific mismatch base pair DNA N-glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mutyh mutY DNA glycosylase enables ISO
ISS
IBA		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:116,664,846...116,676,641
Ensembl chr 4:116,664,920...116,676,637 		JBrowse link
G Pcna proliferating cell nuclear antigen enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28795
    catalytic activity 5723
      catalytic activity, acting on a nucleic acid 649
        catalytic activity, acting on DNA 326
          DNA N-glycosylase activity 14
            mismatch base pair DNA N-glycosylase activity 5
              purine-specific mismatch base pair DNA N-glycosylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 28795
    catalytic activity 5723
      hydrolase activity 2472
        hydrolase activity, acting on glycosyl bonds 145
          hydrolase activity, hydrolyzing N-glycosyl compounds 44
            DNA N-glycosylase activity 14
              mismatch base pair DNA N-glycosylase activity 5
                purine-specific mismatch base pair DNA N-glycosylase activity 2
paths to the root