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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:spleen cancer
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Accession:DOID:672 term browser browse the term
Definition:A lymphatic system cancer that affects white blood cells and involves tumor deposits in the spleen. (DO)
Synonyms:exact_synonym: cancer of spleen;   malignant Splenic tumor;   malignant tumour of spleen;   spleen cancers;   splenic cancer;   splenic cancers
 primary_id: RDO:9003650
 xref: EFO:0007491;   GARD:7683;   ICD10CM:C26.1;   NCI:C3383;   NCI:C3539
For additional species annotation, visit the Alliance of Genome Resources.

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spleen cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAMP2 receptor activity modifying protein 2 ameliorates ISO RGD PMID:31754214 RGD:152985691 NCBI chr16:63,526,915...63,529,697
Ensembl chr16:63,526,305...63,528,767 		JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD79B CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chr16:57,339,492...57,343,085
Ensembl chr16:57,339,457...57,343,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15342
    disease of cellular proliferation 7211
      Neoplasms by Site 6689
        Splenic Neoplasms 3
          spleen cancer 2
            spleen angiosarcoma 0
            splenic manifestation of leukemia + 0
            splenic marginal zone lymphoma 1
Path 2
Term Annotations click to browse term
  disease 15342
    disease of anatomical entity 15027
      Immune & Inflammatory Diseases 5118
        immune system disease 4454
          lymphatic system disease 1653
            splenic disease 149
              Splenic Neoplasms 3
                spleen cancer 2
                  spleen angiosarcoma 0
                  splenic manifestation of leukemia + 0
                  splenic marginal zone lymphoma 1
paths to the root