RAMP2 (receptor activity modifying protein 2) - Rat Genome Database

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Gene: RAMP2 (receptor activity modifying protein 2) Chlorocebus sabaeus
Analyze
Symbol: RAMP2
Name: receptor activity modifying protein 2
RGD ID: 18391520
Description: ENCODES a protein that exhibits coreceptor activity (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); female pregnancy (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); adult respiratory distress syndrome (ortholog); Cardiomegaly (ortholog); FOUND IN adrenomedullin receptor complex (inferred); cell surface (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor activity-modifying protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,526,915 - 63,529,697 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,526,305 - 63,528,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,320,238 - 34,322,154 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,526,915 - 63,529,697 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,526,305 - 63,528,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,320,238 - 34,322,154 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,761,227 - 42,763,041 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,758,447 - 42,763,041 (+)EnsemblGRCh38hg38GRCh38
GRCh371740,913,245 - 40,915,059 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,166,738 - 38,168,585 (+)NCBINCBI36Build 36hg18NCBI36
Build 341738,166,737 - 38,168,580NCBI
Celera1737,569,491 - 37,571,338 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,678,311 - 36,680,158 (+)NCBIHuRef
CHM1_11741,148,776 - 41,150,623 (+)NCBICHM1_1
T2T-CHM13v2.01743,618,368 - 43,620,182 (+)NCBIT2T-CHM13v2.0
Ramp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,137,160 - 101,139,076 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,136,854 - 101,150,372 (+)EnsemblGRCm39 Ensembl
GRCm3811101,246,334 - 101,248,250 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,246,028 - 101,259,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711101,107,648 - 101,109,564 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,062,424 - 101,064,340 (+)NCBIMGSCv36mm8
Celera11112,542,561 - 112,544,477 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1164.47NCBI
Ramp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,689,148 - 86,690,956 (+)NCBIGRCr8
mRatBN7.21086,187,366 - 86,190,692 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,188,812 - 86,231,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,226,790 - 91,228,598 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,701,301 - 90,703,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,094,462 - 86,096,270 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,166,170 - 89,168,962 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,166,890 - 89,168,965 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,965,679 - 88,967,458 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,275,463 - 90,277,242NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,289,832 - 90,291,611NCBI
Cytogenetic Map10q31NCBI
Ramp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545116,584,742 - 16,586,093 (+)NCBIChiLan1.0ChiLan1.0
RAMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,222,750 - 22,225,040 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,112,840 - 24,115,133 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,554,888 - 14,557,175 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,779,666 - 14,781,481 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,779,666 - 14,781,481 (-)Ensemblpanpan1.1panPan2
RAMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,250,711 - 20,252,485 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,712,023 - 19,713,795 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,969,093 - 20,970,865 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,969,095 - 20,971,385 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,753,999 - 19,755,771 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,020,208 - 20,021,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,122,921 - 20,124,693 (-)NCBIUU_Cfam_GSD_1.0
Ramp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,593,351 - 19,595,280 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,479,650 - 17,482,716 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,479,899 - 17,481,788 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,092,196 - 20,094,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,092,204 - 20,094,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,346,948 - 20,349,170 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ramp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247951,435,121 - 1,436,421 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 21
Low 14 39
Below cutoff 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000001363   ⟹   ENSCSAP00000014714
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1663,526,305 - 63,528,767 (-)Ensembl
RefSeq Acc Id: XM_008012599   ⟹   XP_008010790
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,526,915 - 63,528,769 (-)NCBI
Vero_WHO_p1.0NW_02366607734,320,238 - 34,322,154 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008010790 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014714
  ENSCSAP00000014714.1
Reference Protein Sequences
RefSeq Acc Id: XP_008010790   ⟸   XM_008012599
- UniProtKB: A0A0D9S1H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000014714   ⟸   ENSCSAT00000001363


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003335 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001363.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.510 UniProtKB/TrEMBL
InterPro RAMP UniProtKB/TrEMBL
  RAMP_sf UniProtKB/TrEMBL
NCBI Gene RAMP2 ENTREZGENE
PANTHER PTHR14076 UniProtKB/TrEMBL
  RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 UniProtKB/TrEMBL
Pfam RAMP UniProtKB/TrEMBL
UniProt A0A0D9S1H5 ENTREZGENE, UniProtKB/TrEMBL