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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Splenic Neoplasms
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Accession:DOID:9005343 term browser browse the term
Definition:Tumors or cancer of the SPLEEN.
Synonyms:exact_synonym: spleen neoplasm;   spleen neoplasms;   splenic neoplasm
 primary_id: MESH:D013160
 alt_id: RDO:0002787
For additional species annotation, visit the Alliance of Genome Resources.



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Splenic Neoplasms term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26558449 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79b CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17445
    disease of cellular proliferation 7088
      Neoplasms by Site 6730
        Splenic Neoplasms 2
          Littoral Cell Angioma of the Spleen 0
          spleen cancer + 1
Path 2
Term Annotations click to browse term
  disease 17445
    disease of anatomical entity 16777
      Immune & Inflammatory Diseases 4056
        immune system disease 3410
          lymphatic system disease 1339
            splenic disease 141
              Splenic Neoplasms 2
                Littoral Cell Angioma of the Spleen 0
                spleen cancer + 1
paths to the root