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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:aflatoxins-related hepatocellular carcinoma
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Accession:DOID:5022 term browser browse the term
Definition:A hepatocellular carcinoma that develops following exposure to aflatoxin.
Synonyms:xref: NCI:C27922
For additional species annotation, visit the Alliance of Genome Resources.

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aflatoxins-related hepatocellular carcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX1 epoxide hydrolase 1 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535 		JBrowse link
G LOC103223058 glutathione hydrolase light chain 2 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr19:7,353,922...7,406,392 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15388
    disease of cellular proliferation 7341
      cancer 5416
        cell type cancer 3621
          carcinoma 3069
            adenocarcinoma 1560
              hepatocellular carcinoma 864
                aflatoxins-related hepatocellular carcinoma 2
Path 2
Term Annotations click to browse term
  disease 15388
    disease of cellular proliferation 7341
      Neoplasms by Site 6819
        Digestive System Neoplasms 3621
          Gastrointestinal Neoplasms 3504
            gastrointestinal system cancer 2750
              hepatobiliary system cancer 1002
                liver cancer 921
                  liver carcinoma 867
                    hepatocellular carcinoma 864
                      aflatoxins-related hepatocellular carcinoma 2
paths to the root