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Nelson syndrome - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Nelson syndrome
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Accession:DOID:4968 term browser browse the term
Definition:A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
Synonyms:exact_synonym: Nelson's syndrome
 primary_id: MESH:D009347
 xref: GARD:7170;   ICD10CM:E24.1;   NCI:C84917
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Path 1
Term Annotations click to browse term
  disease 287666
    syndrome 132927
      Nelson syndrome 0
Path 2
Term Annotations click to browse term
  disease 287666
    disease of anatomical entity 271341
      nervous system disease 190294
        Nervous System Neoplasms 16219
          Central Nervous System Neoplasms 14277
            Brain Neoplasms 13695
              Supratentorial Neoplasms 5509
                supratentorial cancer 5509
                  diencephalic neoplasm 416
                    hypothalamic neoplasm 416
                      Pituitary Neoplasms 396
                        pituitary gland benign neoplasm 250
                          pituitary adenoma 353
                            functioning pituitary adenoma 188
                              ACTH-secreting pituitary adenoma 40
                                Nelson syndrome 0
paths to the root