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ONTOLOGY REPORT - ANNOTATIONS
Term:Pituitary Neoplasms
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Accession:DOID:9002234 term browser browse the term
Definition:Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
Synonyms:exact_synonym: Pituitary Tumor;   neoplasm of pituitary gland;   pituitary gland neoplasm;   pituitary neoplasm;   pituitary tumors
 primary_id: MESH:D010911
 alt_id: RDO:0006349
For additional species annotation, visit the Alliance of Genome Resources.

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Pituitary Neoplasms term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:11554173
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662821
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:11554173
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:8699506
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:8694115
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:11554173
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:5687177
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1601376
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:10058970
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:11554173
G Il6st interleukin 6 signal transducer JBrowse link 2 44,279,199 44,319,427 RGD:1627046
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:2317360
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1601471
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:11554173
G Pttg1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 10 29,014,332 29,026,088 RGD:68295
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:8547989
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:11038736
ACTH-secreting pituitary adenoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:11554173
RGD:8554872
G Avpr1b arginine vasopressin receptor 1B JBrowse link 13 48,367,307 48,378,831 RGD:14700670
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:11554173
G Usp8 ubiquitin specific peptidase 8 JBrowse link 3 119,173,818 119,222,499 RGD:11554173
RGD:7240710
Familial Isolated Pituitary Adenoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:8554872
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:8554872
growth hormone secreting pituitary adenoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:7240710
RGD:8554872
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662821
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:11554173
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:11554173
G Gpr101 G protein-coupled receptor 101 JBrowse link X 140,296,220 140,303,743 RGD:11554173
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667097
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:13592920
RGD:8554872
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11667097
pituitary adenoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Avpr1b arginine vasopressin receptor 1B JBrowse link 13 48,367,307 48,378,831 RGD:14700668
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792706
PITUITARY ADENOMA 3, MULTIPLE TYPES term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
RGD:7240710
Pituitary Adenoma 5, Multiple Types term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:8554872
RGD:7240710
G LOC100361018 rCG22048-like JBrowse link 20 29,947,427 29,954,869 RGD:8554872
PITUITARY ADENOMA, GROWTH HORMONE-SECRETING, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr101 G protein-coupled receptor 101 JBrowse link X 140,296,220 140,303,743 RGD:7240710
RGD:8554872
pituitary carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:8554872
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:8554872
prolactinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:629544
RGD:11554173
G Cebpd CCAAT/enhancer binding protein delta JBrowse link 11 89,008,008 89,009,146 RGD:11554173
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667097
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:8554872
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:13592920
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7240531
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:629544
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:1625506
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:1642576
RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11667097
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16021
    disease of anatomical entity 15274
      endocrine system disease 4935
        Endocrine Gland Neoplasms 1652
          Pituitary Neoplasms 58
            pituitary cancer + 2
            pituitary gland benign neoplasm + 25
            posterior pituitary gland neoplasm + 0
Path 2
Term Annotations click to browse term
  disease 16021
    disease of anatomical entity 15274
      nervous system disease 10770
        central nervous system disease 8860
          brain disease 8147
            Brain Neoplasms 1292
              Supratentorial Neoplasms 1020
                supratentorial cancer 1020
                  diencephalic neoplasm 60
                    thalamic neoplasm 60
                      hypothalamic neoplasm 60
                        Pituitary Neoplasms 58
                          pituitary cancer + 2
                          pituitary gland benign neoplasm + 25
                          posterior pituitary gland neoplasm + 0
paths to the root

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