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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:central nervous system sarcoma
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Accession:DOID:2133 term browser browse the term
Definition:A central nervous system cancer develops from transformed cells of mesenchymal origin located_in brain and spine, has_material_basis_in abnormally proliferating cells derives_from mesoderm. (DO)
Synonyms:exact_synonym: sarcoma of the CNS
 xref: NCI:C5153
For additional species annotation, visit the Alliance of Genome Resources.


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meninges sarcoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 IMP RGD PMID:27528400 RGD:12738450 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      Neoplasms by Histologic Type 5287
        Connective and Soft Tissue Neoplasms 1895
          sarcoma 286
            central nervous system sarcoma 2
              brain sarcoma + 0
              central nervous system angiosarcoma 0
              central nervous system fibrosarcoma 0
              central nervous system osteosarcoma 0
              central nervous system rhabdomyosarcoma 0
              leptomeninges sarcoma 0
              meninges sarcoma + 2
              spinal cord sarcoma 0
Path 2
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      Neoplasms by Site 7143
        organ system cancer 5262
          nervous system cancer 993
            central nervous system cancer 799
              central nervous system sarcoma 2
                brain sarcoma + 0
                central nervous system angiosarcoma 0
                central nervous system fibrosarcoma 0
                central nervous system osteosarcoma 0
                central nervous system rhabdomyosarcoma 0
                leptomeninges sarcoma 0
                meninges sarcoma + 2
                spinal cord sarcoma 0
paths to the root