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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:childhood acute lymphocytic leukemia
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Accession:DOID:0080144 term browser browse the term
Definition:An acute lymphocytic leukemia occuring during childhood. (DO)
Synonyms:exact_synonym: childhood ALL;   childhood acute lymphoblastic leukemia
 xref: ICD-O:M9835/3;   MONDO:0000870;   NCI:C3168


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childhood acute lymphocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctcf CCCTC-binding factor disease_progression ISO mRNA, protein:increased expression:bone marrow, blood (human) RGD PMID:24393203 RGD:151356757 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18970
    disease of cellular proliferation 7758
      Neoplasms by Histologic Type 5360
        leukemia 626
          lymphoid leukemia 292
            acute leukemia 280
              acute lymphoblastic leukemia 278
                childhood acute lymphocytic leukemia 1
                  childhood B-cell acute lymphoblastic leukemia 0
                  childhood T-cell acute lymphoblastic leukemia 0
Path 2
Term Annotations click to browse term
  disease 18970
    disease of anatomical entity 18265
      Immune & Inflammatory Diseases 5581
        immune system disease 4787
          immune system cancer 669
            lymphatic system cancer 669
              lymphoma 581
                lymphoid leukemia 292
                  acute leukemia 280
                    acute lymphoblastic leukemia 278
                      childhood acute lymphocytic leukemia 1
                        childhood B-cell acute lymphoblastic leukemia 0
                        childhood T-cell acute lymphoblastic leukemia 0
paths to the root