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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:triflupromazine
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Accession:CHEBI:9711 term browser browse the term
Definition:A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position.
Synonyms:exact_synonym: N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine
 related_synonym: 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine;   2-(Trifluoromethyl)promazine;   2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine;   Formula=C18H19F3N2S;   InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3;   InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N;   SMILES=CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F;   trifluopromazine;   triflupromazina;   triflupromazinum
 xref: Beilstein:335308;   CAS:146-54-3;   DrugBank:DB00508;   Drug_Central:2742;   HMDB:HMDB0014650;   KEGG:D00390;   LINCS:LSM-3421
 xref_mesh: MESH:D014273
 xref: PMID:1650428;   PMID:24959397;   Patent:GB813861;   Reaxys:335308;   Wikipedia:Triflupromazine


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triflupromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Triflupromazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      biological role 19808
        antimicrobial agent 18202
          antiviral agent 11072
            anticoronaviral agent 9661
              triflupromazine 1
                triflupromazine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    main group molecular entity 19806
                      s-block molecular entity 19616
                        hydrogen molecular entity 19596
                          hydrides 19108
                            inorganic hydride 18111
                              pnictogen hydride 18100
                                nitrogen hydride 18008
                                  azane 17815
                                    ammonia 17837
                                      organic amino compound 17814
                                        amine 8271
                                          tertiary amine 643
                                            triflupromazine 1
                                              triflupromazine hydrochloride 0
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