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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:triflupromazine
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Accession:CHEBI:9711 term browser browse the term
Definition:A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position.
Synonyms:exact_synonym: N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine
 related_synonym: 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine;   2-(Trifluoromethyl)promazine;   2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine;   Formula=C18H19F3N2S;   InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3;   InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N;   SMILES=CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F;   trifluopromazine;   triflupromazina;   triflupromazinum
 xref: Beilstein:335308;   CAS:146-54-3;   DrugBank:DB00508;   Drug_Central:2742;   HMDB:HMDB0014650;   KEGG:D00390;   LINCS:LSM-3421
 xref_mesh: MESH:D014273
 xref: PMID:1650428;   PMID:24959397;   Patent:GB813861;   Reaxys:335308;   Wikipedia:Triflupromazine



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triflupromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Triflupromazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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  CHEBI ontology 19715
    role 19690
      biological role 19688
        antimicrobial agent 17821
          antiviral agent 10542
            anticoronaviral agent 9073
              triflupromazine 1
                triflupromazine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19715
    subatomic particle 19713
      composite particle 19713
        hadron 19713
          baryon 19713
            nucleon 19713
              atomic nucleus 19713
                atom 19713
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19511
                        hydrogen molecular entity 19504
                          hydrides 18967
                            inorganic hydride 17790
                              pnictogen hydride 17773
                                nitrogen hydride 17658
                                  azane 17428
                                    ammonia 17427
                                      organic amino compound 17427
                                        amine 7922
                                          tertiary amine 629
                                            triflupromazine 1
                                              triflupromazine hydrochloride 0
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