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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:triflupromazine
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Accession:CHEBI:9711 term browser browse the term
Definition:A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position.
Synonyms:exact_synonym: N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine
 related_synonym: 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine;   2-(Trifluoromethyl)promazine;   2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine;   Formula=C18H19F3N2S;   InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3;   InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N;   SMILES=CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F;   trifluopromazine;   triflupromazina;   triflupromazinum
 xref: Beilstein:335308;   CAS:146-54-3;   DrugBank:DB00508;   Drug_Central:2742;   HMDB:HMDB0014650;   KEGG:D00390;   LINCS:LSM-3421
 xref_mesh: MESH:D014273
 xref: PMID:1650428;   PMID:24959397;   Patent:GB813861;   Reaxys:335308;   Wikipedia:Triflupromazine



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triflupromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Triflupromazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term Annotations click to browse term
  CHEBI ontology 19911
    role 19887
      biological role 19885
        antimicrobial agent 18156
          antiviral agent 11028
            anticoronaviral agent 9604
              triflupromazine 1
                triflupromazine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19909
          baryon 19909
            nucleon 19909
              atomic nucleus 19909
                atom 19909
                  main group element atom 19859
                    main group molecular entity 19859
                      s-block molecular entity 19692
                        hydrogen molecular entity 19678
                          hydrides 19156
                            inorganic hydride 18129
                              pnictogen hydride 18118
                                nitrogen hydride 18021
                                  azane 17822
                                    ammonia 17821
                                      organic amino compound 17821
                                        amine 8283
                                          tertiary amine 643
                                            triflupromazine 1
                                              triflupromazine hydrochloride 0
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