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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Apaziquone
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Accession:CHEBI:177558 term browser browse the term
Synonyms:exact_synonym: 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-[(E)-3-hydroxyprop-1-enyl]-1-methylindole-4,7-dione
 related_synonym: Formula=C15H16N2O4;   InChI=1S/C15H16N2O4/c1-16-10(3-2-6-18)9(8-19)13-14(16)12(20)7-11(15(13)21)17-4-5-17/h2-3,7,18-19H,4-6,8H2,1H3/b3-2+;   InChIKey=MXPOCMVWFLDDLZ-NSCUHMNNSA-N;   SMILES=O=C1C(N2CC2)=CC(=O)C=3N(C(=C(C31)CO)/C=C/CO)C
 xref: CAS:114560-48-4;   Chemspider:4710342;   DrugBank:DB12593;   KEGG:D02965
 xref_mesh: MESH:C060817


show annotations for term's descendants           Sort by:
Apaziquone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance EXP NQO1 protein results in increased susceptibility to apaziquone CTD PMID:10910079 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases response to substance ISO SLC2A1 protein results in decreased susceptibility to apaziquone CTD PMID:17520257 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          nitrogen atom 18962
            nitrogen molecular entity 18934
              organonitrogen compound 18783
                organonitrogen heterocyclic compound 18154
                  benzopyrrole 9716
                    indoles 9414
                      Apaziquone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    organic heterobicyclic compound 17233
                                      benzopyrrole 9716
                                        indoles 9414
                                          Apaziquone 2
paths to the root